30779-63-6

Usage

Uses

Used in Pharmaceutical Industry:
6-Bromo-2-methylchromone 97 is used as an intermediate compound for the synthesis of various pharmaceuticals, particularly those with potential therapeutic applications. Its unique chemical structure allows for further functionalization and modification, making it a valuable building block in the development of new drugs.
Used in Chemical Synthesis:
In the field of organic chemistry, 6-Bromo-2-methylchromone 97 serves as a key intermediate for the preparation of other complex organic molecules. One such example is the synthesis of 6-bromochromone-2-carboxaldehyde, which can be achieved through oxidation using selenium dioxide. 6-BROMO-2-METHYLCHROMONE 97 can be further utilized in the development of novel chemical entities with potential applications in various industries.
Used in Research and Development:
6-Bromo-2-methylchromone 97 is also employed in research and development laboratories for studying its chemical properties, reactivity, and potential applications in different fields. Researchers can use 6-BROMO-2-METHYLCHROMONE 97 to explore new reaction pathways, develop innovative synthetic methods, and investigate its biological activities, which may lead to the discovery of new therapeutic agents or other useful applications.

InChI:InChI=1/C10H7BrO2/c1-6-4-9(12)8-5-7(11)2-3-10(8)13-6/h2-5H,1H3

Upstream product

• 207387-68-6 1-(5-bromo-2-hydroxyphenyl)-1,3-butanedione 
• 13298-76-5 tert-butyl 2-diazo-3-oxobutanoate 
• 1761-61-1 5-bromosalicyclaldehyde 
• 89-55-4 5-bromosalicyclic acid 
• 367526-63-4 diethyl 2-{hydroxy[5-bromo-2-(acetoxy)phenyl]methylene}malonate 
• 209461-88-1 ethyl 6-bromo-2-methyl-4-oxo-4H-benzopyran-3-carboxylate 
• 5485-91-6 2-acetoxy-5-bromo-benzoyl chloride 
• 1503-53-3 2-acetyloxy-5-bromobenzoic acid 

Downstream Products

• 105591-52-4 C₁₈H₁₅BrN₂O₃ 
• 925006-67-3 6-(5-bromo-2-hydroxyphenyl)-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 672327-77-4 4-Nitro-benzoic acid [1-(6-bromo-4-oxo-4H-chromen-2-yl)-meth-(Z)-ylidene]-hydrazide 
• 672327-75-2 2-Chloro-benzoic acid [1-(6-bromo-4-oxo-4H-chromen-2-yl)-meth-(Z)-ylidene]-hydrazide 
• 672327-76-3 4-Methoxy-benzoic acid [1-(6-bromo-4-oxo-4H-chromen-2-yl)-meth-(Z)-ylidene]-hydrazide 
• 672327-74-1 4-Chloro-benzoic acid [1-(6-bromo-4-oxo-4H-chromen-2-yl)-meth-(Z)-ylidene]-hydrazide 

Relevant academic research and scientific papers

On-Water Cp?Ir(III)-catalyzed C-H functionalization for the synthesis of chromones through annulation of salicylaldehydes with diazo-ketones

A high-valent Ir(III)-catalyzed C-H bond functionalization is carried out for the first time on water for the synthesis of a biologically relevant chromone moiety. The C-H activation and annulation of salicylaldehydes with diazo-compounds provided the desired chromones. The synthesis of C3-substitution-free chromones has also been demonstrated by a one-pot decarboxylation by employing tert-butyl diazoester. C3 and C5 C-H activations of the product chromone are also carried out under different conditions for further diversification.

On-Water Cp?Ir(III)-Catalyzed C-H Functionalization for the Synthesis of Chromones through Annulation of Salicylaldehydes with Diazo-Ketones

A high-valent Ir(III)-catalyzed C-H bond functionalization is carried out for the first time on water for the synthesis of a biologically relevant chromone moiety. The C-H activation and annulation of salicylaldehydes with diazo-compounds provided the desired chromones. The synthesis of C3-substitution-free chromones has also been demonstrated by a one-pot decarboxylation by employing tert-butyl diazoester. C3 and C5 C-H activations of the product chromone are also carried out under different conditions for further diversification.

Tandem reactions leading to bicyclic pyrimidine nucleosides and benzopyran-4-ones

A novel, rapid, and efficient synthesis of bicyclic pyrimidine nucleosides and benzopyran-4-ones through oxidation of homopropargyl alcohols and subsequent isomerization, intramolecular addition of enol to allenic ketone has been developed. This methodology provides an efficient and promising approach to the structurally and pharmaceutically interesting pyrano[2,3-d]pyrimidine-2,5-dione nucleoside and benzopyran-4-one derivatives.

Microwave-assisted synthesis of functionalized flavones and chromones

A facile microwave synthesis of functionalized flavones and chromones via the cyclization of 1-(2-hydroxyaryl)-3-aryl-1,3-propanedione is described.

A highly practical route to 2-methylchromones from 2-acetoxybenzoic acids

2-Methylchromones were accessed via a keto ester condensation on 2-acetoxybenzoyl chloride, followed by cyclization and decarboxylation. No column chromatography was required in the process.