308087-76-5Relevant academic research and scientific papers
N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists
Wu, Lingyun,Lu, Kai,Desai, Mahesh,Packiarajan, Mathivanan,Joshi, Amita,Marzabadi, Mohammad R.,Jubian, Vrej,Andersen, Kim,Chandrasena, Gamini,Boyle, Noel J.,Walker, Mary W.
, p. 5573 - 5576 (2011)
Subtype specific ligands are needed to evaluate the therapeutic potential of modulating the brain's neuropeptide Y system. The benzothiazepine glycinamide 1a was identified as an NPY5 antagonist lead. While having acceptable solubility, the compound was f
