40334-89-2Relevant academic research and scientific papers
N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists
Wu, Lingyun,Lu, Kai,Desai, Mahesh,Packiarajan, Mathivanan,Joshi, Amita,Marzabadi, Mohammad R.,Jubian, Vrej,Andersen, Kim,Chandrasena, Gamini,Boyle, Noel J.,Walker, Mary W.
scheme or table, p. 5573 - 5576 (2011/10/09)
Subtype specific ligands are needed to evaluate the therapeutic potential of modulating the brain's neuropeptide Y system. The benzothiazepine glycinamide 1a was identified as an NPY5 antagonist lead. While having acceptable solubility, the compound was f
Oxazepines and thiazepines, XXV: Chemical transformations of 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones
Levai
, p. 721 - 726 (2007/10/02)
2,3-Dihydro-1,5-benzothiazepine-4(5H)-thiones 13-22 were prepared by the reaction of the appropriate 2,3-dihydro-1,5-benzothiazepin-4(5H)-ones with Lawesson's reagent. N-Acyl (23-25) and N-alkyl (26-28) derivatives have also been synthesized. Oxidation wi
REACTIONS OF o-AMINOTHIOPHENOL WITH α,β-UNSATURATED DICARBONYL SYSTEMS. FACILE SYNTHESIS OF BENZOTHIAZINES AND BENZOTHIAZEPINES
Balasubramaniyan, V.,Balasubramaniyan, P.,Shaikh, A. S.
, p. 2731 - 2738 (2007/10/02)
When treated with maleanilic/fumaranilic acids or esters or the corresponding imides or isoimides, o-aminothiophenol furnishes benzothiazines, whereas treatment of o-aminothiophenol with acrylic acids/esters furnishes benzothiazepines.The orientational pr
