308256-20-4

Upstream product

• 308255-86-9 (Z)-5-(6-Methyl-1,4,8,11-tetraoxa-dispiro[4.1.4.3]tetradec-6-yl)-pent-2-enoic acid methyl ester 
• 308256-08-8 (Z)-5-(6-Methyl-1,4,8,11-tetraoxa-dispiro[4.1.4.3]tetradec-6-yl)-pent-2-en-1-ol 
• 308255-82-5 3-(6-methyl-1,4,8,11-tetraoxa-dispiro[4.1.4.3]tetradec-6-yl)-propionic acid methyl ester 
• 308255-84-7 3-(6-methyl-1,4,8,11-tetraoxa-dispiro[4.1.4.3]tetradec-6-yl)-propionaldehyde 
• 109064-45-1 2-<2-(methoxycarbonyl)ethyl>-2-methyl-1,3-cyclohexanedione 
• 63488-10-8 4-tert-butylmagnesium bromide 
• 7751-38-4 Diisopropylsilyl dichloride 
• 1193-55-1 2-methylcyclohexane-1,3-dione 
• 308256-14-6 (4-tert-butyl-phenyl)-chloro-diisopropyl-silane 
• 308255-88-1 6-((Z)-5-Chloro-pent-3-enyl)-6-methyl-1,4,8,11-tetraoxa-dispiro[4.1.4.3]tetradecane 

Downstream Products

• 308256-28-2 2-{5-[(4-tert-butyl-phenyl)-diisopropyl-silanyl]-pent-3-enyl}-2-methyl-cyclohexane-1,3-dione 

Relevant academic research and scientific papers

Intramolecular [3+2]-hetero-annulation of allylsilanes with 1,3-cyclohexanediones and its application in the synthesis of hexacyclic hopane triterpenes

In this letter we describe the intramolecular [3+2]-hetero-annulation of allylsilanes with 1,3-cyclohexanediones followed by sila-Wagner-Meerwein shift. The new synthesis of the cyclization precursors offers the advantage to vary the silyl terminator at t