308276-57-5

Usage

Uses

Used in Household Insecticides:
Benzenecarboximidamide, N-(2,2-dimethoxyethyl)is used as an insecticide in household products for its ability to rapidly kill and control various insects, thereby maintaining a hygienic and pest-free environment.
Used in Mosquito Repellents:
Dimefluthrin is utilized as a mosquito repellent in products such as mosquito coils and vaporizer mats to protect against mosquito-borne diseases like malaria, dengue fever, and Zika virus.
Used in Public Health Applications:
In the public health sector, Benzenecarboximidamide, N-(2,2-dimethoxyethyl)is used to control insect vectors, playing a crucial role in preventing the spread of diseases transmitted by insects.
It is essential to handle Dimefluthrin with care and adhere to safety guidelines, as it can pose toxicity risks to humans and animals if not used properly.

Upstream product

• 139721-85-0 α-chlorophenylformamidine hydrochloride 
• 22483-09-6 2,2-dimethoxyethylamine 
• 5873-90-5 methyl benzimidate hydrochloride 
• 100-47-0 benzonitrile 

Downstream Products

• 337969-32-1 3-(2,2-dimethoxyethyl)-2-phenyl-3-hydropyrimidin-4-one 
• 337969-33-2 2-(6-oxo-2-phenylhydropyrimidinyl)ethanol 
• 337969-34-3 2-(6-oxo-2-phenylhydropyrimidinyl)acetic acid 
• 1026395-08-3 N-(1-{hydroxy-[5-(1-methyl-cyclopropyl)-[1,3,4]oxadiazol-2-yl]-methyl}-2-methyl-propyl)-2-(6-oxo-2-phenyl-6H-pyrimidin-1-yl)-acetamide 
• 1395047-01-4 1,6-dihydro-1-[2-(methoxyimino)ethyl]-6-oxo-2-phenyl-5-pyrimidinecarboxylic acid methyl ester 
• 1395047-02-5 1,6-dihydro-1-[2-(methoxyimino)ethyl]-6-oxo-2-phenyl-5-pyrimidinecarboxylic acid 
• 1395047-03-6 3-oxo-1-cyclohexen-1-yl 1,6-dihydro-1-[2-(methoxyimino)ethyl]6-oxo-2-phenyl-5-pyrimidinecarboxylate 
• 1395046-66-8 5-[(2-hydroxy-6oxo-1-cyolohexen-1-yl)carbonyl]-6-oxo-2-phenyl-1(6H)-pyrimidineacetaldehyde 1-(O-methyloxime) 
• 293329-60-9 [5-[(benzyloxycarbonyl)amino]-2-phenyl-6-oxo-1,6-dihydro-1-pyrimidinyl]acetaldehyde dimethyl acetal 
• 148745-95-3 2-(5-amino-6-oxo-2-phenyl-1,6-dihydro-1-pyrimidinyl)-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide 
• 148747-59-5 5-benzyloxycarbonylamino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-ylmethylcarboxylic acid 
• 148747-58-4 [5-[(benzyloxycarbonyl)amino]-2-phenyl-6-oxo-1,6-dihydro-1-pyrimidinyl]acetaldehyde 
• 293329-57-4 1-(2,2-dimethoxyethyl)-6-oxo-2-phenyl-1,6-dihydropyrimidin-5-ylcarboxylic acid 
• 154753-60-3 2-(5-benzyloxycarbonylamino-6-oxo-2-phenyl-1,6-dihydro-1-pyrimidinyl)-N-(3,3,3-trifluoro-1-isopropyl-2-oxopropyl)acetamide 

Relevant academic research and scientific papers

HERBICIDAL BIS-NITROGEN-CONTAINING OXO HETEROCYCLES

Disclosed are compounds of Formula 1, including all stereoisomers, N oxides, and salts thereof, A is a radical selected from the group consisting of, and B1, B2, B3, T, R1, R2 R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and R13 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

Development of orally active nonpeptidic inhibitors of human neutrophil elastase

5-Amino-2-phenylpyrimidin-6-ones, some of their desamino derivatives, and miscellaneous derivatives were synthesized and biologically evaluated on both in vitro activity and oral activity in an acute hemorrhagic assay. These compounds contained an α-keto-1,3,4-oxadiazole moiety to bind covalently to the Ser-195 hydroxy group of human neutrophil elastase (HNE). Among those tested, compounds 11a-c,e,i-l(F), 11d,e,k(H), 21d,e,k(F), and 21d,e(H) showed a good oral profile. RS-Mixture 3(H) was selected for clinical evaluation based on its oral potency, duration of action, enzyme selectivity, safety profile, and ease of synthesis. Structure -activity relationships (SARs) are discussed.

Nonpeptidic inhibitors of human leukocyte elastase. 5. Design, synthesis, and X-ray crystallography of a series of orally active 5-aminopyrimidin-6- one-containing trifluoromethyl ketones

The effects of changes in substitution in a series of 5-amino-2- pyrimidin-6-ones on both in vitro activity and oral activity in an acute hemorrhage assay have been explored. These compounds contained either a trifluoromethyl ketone or a boronic acid moiety to bind covalently to the Ser-195 hydroxyl of human leukocyte elastase (HLE). Boronic acid-containing inhibitors were found to be more potent than the corresponding trifluoromethyl ketones in vitro but were less active upon oral administration. Compound 13b was found to offer the best combination of oral potency, duration of action, and enzyme selectivity and, as such, was selected for further biological testing. X-ray crystallography of a cocrystallized complex of compound 19m and porcine pancreatic elastase demonstrated that the inhibitor is bound to the enzyme in a manner similar to that found previously for a closely related series of pyridone-containing inhibitors of HLE.