308368-00-5Relevant academic research and scientific papers
Role of hydrophobic interactions in binding S-(N-aryl/alkyl-N-hydroxycarbamoyl)glutathiones to the active site of the antitumor target enzyme glyoxalase I
Kalsi,Kavarana,Lu,Whalen,Hamilton,Creighton
, p. 3981 - 3986 (2007/10/03)
Hydrophobic interactions play an important role in binding S-(N-aryl/alkyl-N-hydroxycarbamoyl)glutathiones to the active sites of human, yeast, and Pseudomonas putida glyoxalase I, as the log K(i) values for these mechanism-based competitive inhibitors de
