308386-31-4Relevant academic research and scientific papers
Selective, orally active MMP inhibitors with an aryl backbone
Barta, Thomas E.,Becker, Daniel P.,Bedell, Louis J.,De Crescenzo, Gary A.,McDonald, Joseph J.,Mehta, Pramod,Munie, Grace E.,Villamil, Clara I.
, p. 2481 - 2483 (2001)
This letter describes SAR exploration and rat PK optimization of a series of novel, MMP-1 sparing aryl hydroxamate sulfonamides with activity against MMP-2 and MMP-13.
