30839-23-7

Upstream product

• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 7380-78-1 4-(phenylethynyl)anisole 
• 19172-47-5 Lawessons reagent 
• 30839-20-4 1,4-bis(4-methoxyphenyl)-2,3-diphenylbutane-1,4-dione 

Relevant academic research and scientific papers

Oxygen as a Crucial Comonomer in Alkyne-Based Polymerization toward Functional Poly(tetrasubstituted furan)s

Oxygen (O2), one of the most essential gases, is abundant, cheap, nontoxic, and environmentally friendly. However, O2 has not been used as a monomer to synthesize polymers yet, probably because of the difficulty in chain growth. In this paper, we develop a new alkyne-based polymerization in which O2 serves as a comonomer under mild reaction conditions. Functionalized diynes could react with O2 in the presence of Pd(OAc)2/ZnCl2 in N,N-dimethylacetamide (DMAc) and perfluorodecalin under atmospheric oxygen. Soluble poly(tetrasubstituted furan)s with high weight-average molecular weights (Mw up to 14 900) were obtained in high yields (up to 86%). The ratio of isomeric repeating units of P1(m) can be identified by analyzing the components of model reaction products. Moreover, P1(6) could function as a fluorescent sensor for explosive detection with superamplification quenching effect. P2-P5 with conjugated structures possess large two-photon absorption cross sections up to 1570 GM, showing great potential as two-photon absorption materials. Thus, this work not only establishes a powerful O2-involved alkyne-based polymerization but also provides poly(tetrasubstituted furan)s with versatile properties, which are potentially applicable in optoelectronic and biological fields.

Silver-Catalyzed Coupling of Two Csp3-H Groups and One-Pot Synthesis of Tetrasubstituted Furans, Thiophenes, and Pyrroles

Silver-catalyzed coupling of two Csp3-H groups to form 1,4-diketones have been developed for the first time. The resultant ketones then undergo cyclization to synthesize tetrasubstituted furans, thiophenes, and pyrroles from benzyl ketone derivatives in a one-pot reaction process. This highly-efficient synthetic method, which utilizes air as the terminal oxidant and readily accessible starting materials, displays a wide substrate scope and broad functional-group tolerance.

Copper(II)-promoted C-C bond formation by oxidative coupling of two C(sp3)-H bonds adjacent to carbonyl group to construct 1,4-diketones and tetrasubstituted furans

The copper(II)-promoted C-C bond formation from the coupling of two C(sp3)-H bonds that are adjacent to a carbonyl group was achieved. This protocol offers a simple and efficient approach to 2,3-disubstituted 1,4-diketones and tetrasubstituted furans. This method features a wide substrate scope and high functional group tolerance.

Reaction of 2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulphide with Substituted Butane-1,4-diones: Part II - Novel Synthesis of Substituted Thiophenes and Furans

The reaction of substituted butane-1,4-diones (2) with 2,4-bis(4-methoxyphenyl)1,3,2,4-dithiadiphosphetane-2,4-disulphides (1; Lawesson reagent) has been investigated.While the reaction of 1,2-diacylethane (2k) with 1 leads exclusively to the formation of the corresponding 2,5-disubstituted thiophene (4k) in excellent yield, the interaction of tri- and tetrasubstituted butane-1,4-diones (2a-j) with 1 under identical conditions invariably results in the formation of a mixture of the corresponding thiophenes (4) and furans (3) in varying proportions.The identity of 3 and 4 and also their molar percentages in the product mixtures have been established by GLC and PMR spectral analyses.