3088-79-7

Usage

Uses

Used in Organic Synthesis:
N-Dodecylboronic acid is used as a reagent in organic synthesis for its ability to selectively form stable boronate esters with diols, facilitating the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-Dodecylboronic acid is utilized as a building block for the development of new pharmaceutical compounds, taking advantage of its reactivity and stability.
Used in Analytical Chemistry:
N-Dodecylboronic acid is used as a selective and sensitive reagent for the determination of diol-containing compounds in biological and environmental samples, enhancing the accuracy of analytical methods.
Used in Sensor Development:
N-Dodecylboronic acid is employed in the development of sensors and detection methods for sugars such as glucose and fructose, contributing to advancements in diagnostic and monitoring technologies.
Used in Drug Delivery Systems:
In the pharmaceutical industry, N-Dodecylboronic acid is used as a component in drug delivery systems to improve the targeting and efficiency of drug administration, potentially enhancing therapeutic outcomes.
Used in Material Science:
N-Dodecylboronic acid is utilized in the development of new materials and catalysts, leveraging its unique chemical properties to create innovative products with improved performance characteristics.
Overall, N-Dodecylboronic acid's diverse applications across various industries highlight its importance and potential in scientific research and commercial development.

InChI:InChI=1/C12H27BO2/c1-2-3-4-5-6-7-8-9-10-11-12-13(14)15/h14-15H,2-12H2,1H3

Upstream product

• 688-74-4 boric acid tributyl ester 
• 18996-28-6 dodecylmagnesium chloride 
• 121-43-7 Trimethyl borate 
• 143-15-7 1-dodecylbromide 
• 177035-82-4 2-dodecyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 112-41-4 1-dodecene 

Downstream Products

• 1179810-87-7 1-(3-dodecylphenyl)-1-hydroxy-1,2-dihydropyrrolo[3,4-c]pyridine-3-one 
• 62155-38-8 1,1-diphenyl-tetradec-1-ene 
• 112-53-8 1-dodecyl alcohol 
• 519054-11-6 4-dodecyl-1-(trimethylsilyl)benzene 
• 170698-90-5 1-dodecyl-4-iodobenzene 
• 1315305-64-6 methyl 5-dodecyl-3-(5-dodecyl-3-(5-dodecyl-3-(5-dodecyl-2-fluoro-3-nitrobenzamido)-2-fluorobenzamido)-2-fluorobenzamido)-2-fluorobenzoate 
• 1315305-62-4 methyl 5-dodecyl-3-(5-dodecyl-2-fluoro-3-nitrobenzamido)-2-fluorobenzoate 
• 1315305-61-3 5-dodecyl-2-fluoro-3-nitrobenzoic acid 
• 1315305-60-2 methyl 5-dodecyl-2-fluoro-3-nitrobenzoate 
• 112-40-3 dodecane 

Relevant academic research and scientific papers

MACROCYLCES COMPRISING A 4-AMIDO-2,4-PENTADIENOATE MOIETY FOR THE TREATMENT OF HYPOXIC CANCERS

The present disclosure provides macrocyclic compounds comprising a 4-amido- 2,4-pentadienoate (APD) moiety. The compounds exhibit toxicity that is selective to the hypoxic micro-environments often found in cancerous tissues. The disclosed compounds are therefore suitable for treatment of hypoxic cancer cells.

FLUORESCENCE DETECTION OF POISON OAK OIL

The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut.

Tuning the optical and electronic properties of 4,8-disubstituted benzobisoxazoles via alkyne substitution

In an effort to design new electron-deficient building blocks for the synthesis of conjugated materials, a series of new trans-benzobisoxazoles bearing halogen or alkynyl substituents at the 4,8-positions was synthesized. Additionally, the impact of these modifications on the optical and electronic properties was investigated. Theoretical calculations predicted that the incorporation of various alkynes can be used to tune the energy levels and band gaps of these small molecules. The targeted 4,8-disubstituted benzobisoxazoles were easily prepared in good yields using a two-step reaction sequence: Lewis acid catalyzed orthoester cyclization followed by Sonogashira cross-coupling. The experimentally determined HOMO values for these 4,8-disubstituted benzobisoxazoles ranged from -4.97 to -6.20 eV and showed reasonable correlation to the theoretically predicted values, with a percent deviation that ranged from 2.4-12.8%. However, the deviation between actual and predicted HOMO values was reduced to less than 3.5% when the theoretical values were extrapolated to the long-chain limit and compared to copolymers containing the 4,8-disubstituted benzobisoxazoles. Collectively, these results indicate that these 4,8-disubstituted trans-benzobisoxazoles can be used for the synthesis of new conjugated materials with electronic properties that are variable and predictable.

Planar macrocyclic fluoropentamers as supramolecular organogelators

Despite their great diversities, 2D-shaped macrocycles that can serve as the organogelators have been surprisingly rare; two planar macrocyclic fluoropentamers designed by us were highly able to gelate organic solvents, largely derived from their strong tendency to form 1D stacked fibrillar structures stabilized by both interplanar H-bonds and π-π stacking forces.