30962-69-7

Usage

Uses

Used in Pharmaceutical Industry:
2-BENZO[B]THIOPHEN-2-YL-ETHANOL is used as a building block or intermediate for the synthesis of various pharmaceuticals due to its unique chemical structure and properties. It contributes to the development of new drugs with potential therapeutic properties.
Used in Organic Compounds Synthesis:
2-BENZO[B]THIOPHEN-2-YL-ETHANOL is used as a key intermediate in the synthesis of various organic compounds, enabling the creation of a wide range of chemical products with diverse applications.
Used in Solvent Applications:
2-BENZO[B]THIOPHEN-2-YL-ETHANOL is used as a solvent in various chemical processes, providing a suitable medium for reactions to occur, and facilitating the synthesis of target compounds.
Used in Pesticide Production:
2-BENZO[B]THIOPHEN-2-YL-ETHANOL is used in the production of pesticides, contributing to the development of effective and environmentally friendly pest control solutions.
Used in Fine Chemicals Industry:
2-BENZO[B]THIOPHEN-2-YL-ETHANOL is used in the production of other fine chemicals, which are high-purity, specialty chemicals used in various industries, including pharmaceuticals, agriculture, and materials science.
Additionally, 2-BENZO[B]THIOPHEN-2-YL-ETHANOL has been studied for its potential pharmacological activities and therapeutic properties, indicating its potential use in the development of new treatments and therapies in the future.

Upstream product

• 75-21-8 oxirane 
• 50779-55-0 benzothiophen-2-yllithium 
• 1072-53-3 ethyleneglycol sulfate 
• 95-15-8 Benzo[b]thiophene 
• 29199-11-9 2-formylthiophenol 
• 17890-55-0 ethyl benzo[b]thiophene-2-carboxylate 
• 6314-28-9 benzo[b]thiophene-2-carboxylic acid 

Downstream Products

• 7136-60-9 2-(2-chloro-ethyl)-benzo[b]thiophene 
• 40412-10-0 2-(1-benzothien-2-yl)ethyl 4-methylbenzenesulfonate 
• 344305-20-0 3-Bromo-2-(β-hydroxyethyl)benzothiophene 
• 4565-08-6 N-(2-benzo[b]thiophen-2-yl-ethyl)-benzamide 
• 858821-54-2 1-phenyl-3,4-dihydro-benzo[4,5]thieno[3,2-c]pyridine 
• 126312-03-6 2-(benzo[b]thiophen-2-yl)ethanamine 

Relevant academic research and scientific papers

Copper-Catalyzed Cascade Cyclization of Indolyl Homopropargyl Amides: Stereospecific Construction of Bridged Aza-[n.2.1] Skeletons

Catalytic cycloisomerization-initiated cascade cyclizations of terminal alkynes have received tremendous interest, and been widely used in the facile synthesis of a diverse array of valuable complex heterocycles. However, these tandem reactions have been mostly limited to noble-metal catalysis, and are initiated by an exo-cyclization pathway. Reported herein is an unprecedented copper-catalyzed endo-cyclization-initiated tandem reaction of indolyl homopropargyl amides, where copper catalyzes both the hydroamination and Friedel–Crafts alkylation process. This method allows the practical and atom-economical synthesis of valuable bridged aza-[n.2.1] skeletons (n=3–6) with wide substrate scope, and excellent diastereoselectivity and enantioselectivity by a chirality-transfer strategy. Moreover, the mechanistic rationale for this novel cascade cyclization is also strongly supported by control experiments, and is distinctively different from the related gold catalysis.

Methods of treating soft tissue defects

The specification discloses compositions and methods for treating a soft tissue defect of an individual.

COMPOSITIONS AND IMPROVED SOFT TISSUE REPLACEMENT METHODS

The present specification discloses compositions and methods of transplanting tissue useful for treating a soft tissue condition of an individual.

2,3,4-Substituted cyclopentanones as therapeutic agents

Disclosed herein are compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, wherein a dashed line represents the presence or absence of a bond; Y is a carboxylic acid, sulfonic acid, or phosphonic acid functional group; or an amide or ester thereof comprising from 0 to 12 carbon atoms; or Y is hydroxymethyl or an ether thereof comprising from 0 to 12 carbon atoms; or Y is a tetrazolyl functional group; A is —(CH2)6—, cis —CH2—CH═CH—(CH2)3—, or —CH2—C≡C—(CH2)3— wherein 1 or 2 carbons may be substituted with S or O; B is hydrogen, C1-6 hydrocarbyl, CN, CO2H, or —(CH2)mX(CH2)pH, wherein m is at least 1 and the sum of m and p is from 1 to 5; X is S or O; J is H, CH3, or CF3; D is a covalent bond, CH2, O, or S; and E is an aromatic heterobicyclic ring system which may have substituents comprising up to 6 non-hydrogen atoms each. Methods, compositions, and medicaments related thereto are also disclosed.

Sleep inducing compounds and methods relating thereto

Compounds having the following structure (I): including stereoisomers, prodrugs, and pharmaceutically acceptable salts, esters and solvates thereof, wherein R1, R2, R3a, R3b, L1, L2 and n are as defined herein. Such compounds generally function as H1 receptor ligands, and thus have utility as sleep inducing agents. Pharmaceutical compositions containing a compound of structure (I), as well as methods relating to the use thereof, are also disclosed.

Triflic anhydride-promoted cyclization of sulfides: A convenient synthesis of fused sulfur heterocycles

A new approach to the synthesis of annulated sulfur heterocycles based on triflic anhydride-promoted cyclization of the hetaryl(aryl) containing alkyl sulfides was elaborated. Smooth demethylation of initially formed cyclic sulfonium salts by treatment with triethylamine afforded a number of five-, six- and seven-membered fused sulfur heterocycles. Unexpected ring opening took place in the reaction of diethylamine with 5-membered sulfonium salts.

New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central α2-antagonistic activity as potential antidepressants

The synthesis and biological activity of a series of benzofuro[3,2- c]pyridines and a benzothieno[3,2-c]pyridine are described. These compounds exhibit high affinity for the α2-adrenoceptor, with high selectivity versus the α1-receptor. Compound 1 also shows potent in vivo central activity and has been selected for further biological and clinical evaluation.