3097-72-1Relevant academic research and scientific papers
NOUVELLE VOIE D'ACCES AUX COMPOSES CARBONYLES α-ALLENIQUES
Bernard, Didier,Doutheau, Alain,Gore, Jacques
, p. 2721 - 2732 (1987)
Several α-allenic ketones and aldehydes 1 have been synthesised from monosubstituted acetylenic compounds 2 and α-carbonyl ketals 3.The key step is the reaction of propargylic mesylates 5 with a Grignard reagent in the presence of CuBr.The sequence is app
