30983-80-3

Basic information

• Product Name: 1,5-bis(3,4-dichlorophenyl)penta-1,4-dien-3-one
• CAS NO: 30983-80-3
• Molecular Formula: C₁₇H₁₀Cl₄O
• Molecular Weight: 372.0727
• Mol File: 30983-80-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 527.9°C at 760 mmHg
• Flash Point: 220.1°C
• Density: 1.427g/cm³
• Vapor Pressure: 3.12E-11mmHg at 25°C
• Refractive Index: 1.668
• CAS DataBase Reference: 1,5-bis(3,4-dichlorophenyl)penta-1,4-dien-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-bis(3,4-dichlorophenyl)penta-1,4-dien-3-one(30983-80-3)
• EPA Substance Registry System: 1,5-bis(3,4-dichlorophenyl)penta-1,4-dien-3-one(30983-80-3)

Safety Data

• Hazardous Substances Data: 30983-80-3(Hazardous Substances Data)

Usage

Explanation

Different sources of media describe the Explanation of 30983-80-3 differently. You can refer to the following data:
1. The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 18 carbon (C) atoms, 10 hydrogen (H) atoms, 4 chlorine (Cl) atoms, and 1 oxygen (O) atom.
2. Pentadienones are a class of organic compounds that have a five-carbon chain and a ketone group. This compound belongs to this family due to its structure.
3. The compound is a yellow-colored solid, which is a physical property describing its appearance.
4. This property describes the compound's ability to dissolve in different solvents. It is not soluble in water but can dissolve in organic solvents like alcohols, ethers, and hydrocarbons.
5. Due to its unique structure and reactivity, this compound is used as a starting material or intermediate in the synthesis of various pharmaceuticals and agrochemicals.
6. The compound's properties make it a valuable building block for the synthesis of more complex molecules, which can be used in organic chemistry research.
7. The compound's reactivity allows it to be used as a starting point for creating more complex molecules, which can have various applications in different fields.

Chemical family

Pentadienones

Appearance

Yellow solid

Solubility

Insoluble in water, soluble in organic solvents

Applications

Synthesis of pharmaceuticals and agrochemicals

Potential applications

Organic chemistry research

Reactivity

Used as a building block for complex molecule synthesis

Upstream product

• 67-64-1 acetone 
• 6287-38-3 3,4-dichlorobenzaldehyde 

Relevant articles and documents

Synthesis and synergistic antifungal effects of monoketone derivatives of curcumin against fluconazole-resistant Candida spp.

Twenty-three monoketone derivatives of curcumin were synthesized to investigate the synergy with fluconazole against fluconazole-resistant Candida spp. The minimal inhibitory concentration (MIC80) and the fractional inhibitory concentration index (FICI) of the antifungal synergist fluconazole were measured against fluconazole-resistant C. albicans, C. tropicalis and C. krusei in vitro. Most of these compounds showed good synergistic activities against C. tropicalis. Among them, compound 9 exhibited significant synergistic activities against Candida spp. SARs were also discussed. In particular, a cell growth test exhibited that a combination of 1 μg ml-1 fluconazole and 64 μg ml-1 or 128 μg ml-1 compound 9 showed the most potent fungicidal effect against C. tropicalis. The synergistic effect may be associated with the changes of the intracellular ATP content and cell membrane permeability. Our results provided a basis for future evaluation and development of these compounds as leads for therapeutics for fluconazole-resistant candidiasis.

(Dichlorophenyl)alkenones and their oximes (author's transl)

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