309926-39-4Relevant academic research and scientific papers
New tetracyclic tacrine analogs containing pyrano[2,3-c]pyrazole: Efficient synthesis, biological assessment and docking simulation study
Khoobi, Mehdi,Ghanoni, Farzaneh,Nadri, Hamid,Moradi, Alireza,Hamedani, Morteza Pirali,Moghadam, Farshad Homayouni,Emami, Saeed,Vosooghi, Mohsen,Zadmard, Reza,Foroumadi, Alireza,Shafiee, Abbas
, p. 296 - 303 (2015)
A new series of tacrine-based acetylcholinesterase (AChE) inhibitors 7a-l were designed by replacing the benzene ring of tacrine with aryl-dihydropyrano[2,3-c]pyrazole. The poly-functionalized hybrid molecules 7a-l were efficiently synthesized through mul
Glycine-catalyzed efficient synthesis of pyranopyrazoles via one-pot multicomponent reaction
Reddy, M. B. Madhusudana,Jayashankara,Pasha
experimental part, p. 2930 - 2934 (2010/10/19)
A facile and convenient protocol is developed for the fast (5-20min) and high-yielding (85-95%) synthesis of fused pyranopyrazoles from ethyl acetoacetate, hydrazine hydrate, an aldehyde, and malononitrile in the presence of nontoxic, simple, and readily available organocatalyst glycine in aqueous medium at 25°C.
Rapid four-component reactions in water: synthesis of pyranopyrazoles
Vasuki, Gnanasambandam,Kumaravel, Kandhasamy
, p. 5636 - 5638 (2008/12/22)
An environmentally benign four-component reaction in aqueous medium at room temperature has been developed for the synthesis of 6-amino-5-cyano-3-methyl-4-aryl/heteroaryl-2H,4H-dihydropyrano[2,3-c]pyrazoles.
