31009-31-1 Usage
General Description
8-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline is a synthetic chemical compound that falls under the category of fluoroquinolone antibiotics. It consists of a quinoline ring with a fluorine atom and a hydroxyl group attached, as well as a trifluoromethyl group. These chemical features contribute to its antimicrobial and antibacterial properties, making it effective in the treatment of various bacterial infections. Its unique structure and properties make it a valuable tool in the development of new antibiotics and pharmacological research.
Check Digit Verification of cas no
The CAS Registry Mumber 31009-31-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,0,0 and 9 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 31009-31:
(7*3)+(6*1)+(5*0)+(4*0)+(3*9)+(2*3)+(1*1)=61
61 % 10 = 1
So 31009-31-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H5F4NO/c11-6-3-1-2-5-7(16)4-8(10(12,13)14)15-9(5)6/h1-4H,(H,15,16)
31009-31-1Relevant articles and documents
Selective and efficient structural elaboration of 2-(trifluoromethyl)quinolinones
Marull, Marc,Schlosser, Manfred
, p. 1576 - 1588 (2007/10/03)
The acid-catalyzed cyclization-condensation between anilines and ethyl 4,4,4-trifluoroacetoacetate affords 1,4-dihydro-2-trifluoromethyl-4H-4-quinolinones (1), which can easily be converted into 4-bromo-2-(trifluoromethyl)quinolines. These undergo halogen/metal exchange, generating 2-trifluoromethyl-4-quinolyllithiums, when treated with butyllithium, and hydrogen/metal exchange, generating 4-bromo-2-trifluoromethyl-3-quinolyllithiums, when treated with lithium diisopropylamide. Trapping of the latter intermediates provides 3-functionalized products that may be further elaborated by electrophilic substitution of the bromine atom. A few unexpected findings resulted from these investigations, the most noteworthy being an unprecedented buttressing effect and a counterintuitive halogen reactivity. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
