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5-Nitro-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione, also known as 5-nitro-2'-deoxyuridine, is a chemical compound derived from the nucleoside 2'-deoxyuridine. It features a pyrimidine base attached to a pentofuranosyl sugar moiety, with a nitro group at the 5-position of the pyrimidine ring. 5-nitro-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione is of interest in the field of medicinal chemistry, particularly in the study of antiviral agents and DNA synthesis inhibitors. The nitro group confers unique chemical and biological properties to the molecule, potentially affecting its interaction with enzymes and other biomolecules. Research on such compounds can provide insights into the development of new therapeutic strategies for viral infections and other diseases.

3106-03-4

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3106-03-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3106-03-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,0 and 6 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3106-03:
(6*3)+(5*1)+(4*0)+(3*6)+(2*0)+(1*3)=44
44 % 10 = 4
So 3106-03-4 is a valid CAS Registry Number.

3106-03-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-nitro-2,4(1H,3H)-pyrimidinedione

1.2 Other means of identification

Product number -
Other names 5-NITROURACIL extrapure

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3106-03-4 SDS

3106-03-4Downstream Products

3106-03-4Relevant academic research and scientific papers

5-Nitro-2'-deoxyuridine 5'-Phosphate: A Mechanism-Based Inhibitor of Thymidylate Synthetase

Maggiora, Linda,Chang, Charles C. T.-C.,Torrence, Paul F.,Mertes, Mathias P.

, p. 3192 - 3198 (1981)

5-Nitro-2'-deoxyuridine 5'-phosphate (2) was found to be a mechanism-based affinity label for thymidylate synthetase purified from amethopterin resistant Lactobacillius casei.The inhibition proceeds in two steps via the initial formation of the noncovalent complex 3 (Ki = 510-7 M) which is converted to the covalent complex 4. The net dissociation constant for the overall sequence is 6.510-10 M, a value predicted from model studies of the bimolecular reaction of 2-mercaptoethanol with 5-nitrouridine or 2.

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