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4-Phenyl-2-(trifluoromethyl)oxazol-5(4H)-one is a chemical compound with the molecular formula C10H6F3NO2. It is a heterocyclic compound, specifically an oxazolone derivative, featuring a phenyl group at the 4-position and a trifluoromethyl group at the 2-position. 4-phenyl-2-(trifluoromethyl)oxazol-5(4H)-one is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals due to its unique structure and reactivity. It can be used as a building block or intermediate in the preparation of various biologically active molecules, such as inhibitors, antagonists, and other therapeutic agents. The presence of the trifluoromethyl group enhances the lipophilicity and metabolic stability of the molecule, which can be beneficial in drug design.

3108-27-8

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3108-27-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3108-27-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,1,0 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 3108-27:
(6*3)+(5*1)+(4*0)+(3*8)+(2*2)+(1*7)=58
58 % 10 = 8
So 3108-27-8 is a valid CAS Registry Number.

3108-27-8Relevant academic research and scientific papers

A tandem [3+2] cycloaddition-elimination cascade reaction to generate pyrrolo-[3,4-c]pyrrole-1,3-diones

Martinez-Ariza, Guillermo,Dietrich, Justin,De Moliner, Fabio,Hulme, Christopher

, p. 1801 - 1804 (2013/09/12)

An efficient tandem [3+2] cycloaddition-elimination cascade sequence has been developed enabling assembly of the pharmacologically relevant pyrrolo-[3,4-c]pyrrole-1,3-dione chemotype. The strategy involves simple mixing of readily accessible oxazolin-2-on

Application of a novel [3+2] cycloaddition reaction to prepare substituted imidazoles and their use in the design of potent DFG-out allosteric B-Raf inhibitors

Dietrich, Justin,Gokhale, Vijay,Wang, Xiadong,Hurley, Laurence H.,Flynn, Gary A.

experimental part, p. 292 - 304 (2010/04/02)

B-Raf protein kinase, which is a key signaling molecule in the RAS-RAF-MEK-ERK signaling pathway, plays an important role in many cancers. The B-Raf V600E mutation represents the most frequent oncogenic kinase mutation known and is responsible for increas

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