3108-67-6

Upstream product

• 16417-65-5 2,4,6-trichlorophenyl trifluoroacetate 
• 16741-80-3 S-benzyl-L-cysteine methyl ester hydrochloride 
• 67-56-1 methanol 
• 329-52-2 S-benzyl-N-trifluoroacetyl-L-cysteine 
• 186581-53-3 diazomethane 

Downstream Products

• 128010-08-2 S-benzyl-N-trifluoracetyl-L-cysteine sulfoxide methyl ester 
• 128010-09-3 S-benzyl-N-trifluoracetyl-L-cysteine sulfone methyl ester 
• 1492-83-7 N,N'-bis(trifluoroacetyl)-L-cystine dimethyl ester 
• 128010-12-8 (Z)-methyl N-trifluoracetyl-3-benzylthio-2-amino-2-propenoate 
• 128010-13-9 (E)-methyl N-trifluoracetyl-3-benzylthio-2-amino-2-propenoate 

Relevant academic research and scientific papers

Fluorination of sulfur-containing amino acids: Reaction of xenon difluoride with cysteine derivatives

The reaction of XeF2 with cysteine derivatives RSCH2CH(NHR)COOR, i.e., S-benzyl-N-trifluoroacetyl-L-cysteine methyl ester, S-benzyl-N-carbobenzoxy-L-cysteine p-nitrophenyl ester, and S-methyl-N-trifluoroacetyl-L-cysteine methyl ester is described.The fluorinated products PhCHFSCH2CH(NHR)COOR, PhCH2SCHFCH(NHR)COOR, and FCH2SCH2CH(NHR)COOR were identified by 1H and 19F nuclear magnetic resonance spectroscopy.PhCH2SCHFCH(NHR)COOR loses HF within 24 hours to give Z- and E-PhCH2SCH=C(NHR)COOR.If the reaction with XeF2 is carried out in the presence of moisture the sulfoxide RS(O)CH2CH(NHR)COOR and sulfone RSO2CH2CH(NHR)COOR are produced.