310888-52-9Relevant academic research and scientific papers
Transformations of phenylhydrazones of 5-acyl-1,2,4-triazines to pyrazolo[4,3-e][1,2,4]triazines or 4-cyanopyrazole
Mojzych, Mariusz,Rykowski, Andrzej
, p. 1003 - 1007 (2007)
(Chemical Equation Presented) A simple and high yielding preparation of pyrazolo[4,3-e][1,2,4]triazines and 4-cyano-3-methyl-1-phenylpyrazole derivatives from corresponding phenylhydrazones of 5-acyl-1,2,4-triazines by melt under acidic medium and by ther
Direct synthesis of pyrazolo[4,3-e][1,2,4]triazine derivatives from oximes of 5-acyl and 5-formyl-1,2,4-triazines
Mojzych, Mariusz,Rykowski, Andrzej
, p. 191 - 194 (2006)
Deprotection of carbonyl functionality in oximes of 5-acyl and 5-formyl-1,2,4-triazines followed by condensation with hydrazine or substituted hydrazine and subsequent intramolecular ring closure of the resulting hydrazones of 5-acyl and 5-formyl-1,2,4-tr
A new synthesis of pyrazolo[4,3-e][1,2,4]triazines via acid promoted ring closure of the phenylhydrazones of 5-acyl-1,2,4-triazines
Rykowski, Andrzej,Mojzych, Mariusz,Karczmarzyk, Zbigniew
, p. 2175 - 2181 (2007/10/03)
The reaction of various substituted phenylhydrazones of 5-acyl-1,2,4-triazines in the presence of 1.1 equivalent of HCl in boiling ethanol-dioxane mixture has been studied. In all reactions the formation of the corresponding pyrazolo[4,3-e][1,2,4]triazines (3a-r) takes place in good yield. The structures of 3a-r were unequivocally established by spectroscopic methods as well as by X-Ray analysis of selected 5-methyl-3-phenyl-7-(p-tolyl)pyrazolo[4,3-e][1,2,4]triazine (3a).
