31112-92-2 Usage
Uses
Used in Pharmaceutical Industry:
(2-PYRIDIN-4-YL-THIAZOL-4-YL)-ACETIC ACID is used as an anti-inflammatory agent for its ability to inhibit the cyclooxygenase enzyme, which plays a crucial role in the production of prostaglandins responsible for inflammation. This property makes it a promising candidate for the development of drugs to treat various inflammatory conditions.
(2-PYRIDIN-4-YL-THIAZOL-4-YL)-ACETIC ACID is also used as an analgesic agent due to its potential to alleviate pain by inhibiting the enzyme responsible for prostaglandin synthesis, thereby reducing inflammation and pain associated with various conditions.
Used in Research and Development:
In the field of scientific research, (2-PYRIDIN-4-YL-THIAZOL-4-YL)-ACETIC ACID serves as a valuable compound for studying its potential therapeutic applications in various medical conditions. Its unique chemical structure and biological activities make it an interesting subject for further exploration and development of new drugs with improved efficacy and safety profiles.
Used in Drug Discovery:
(2-PYRIDIN-4-YL-THIAZOL-4-YL)-ACETIC ACID is utilized in drug discovery processes as a lead compound for the development of novel therapeutic agents. Its ability to inhibit the cyclooxygenase enzyme and exhibit anti-inflammatory and analgesic properties makes it a promising starting point for the design and synthesis of new drugs targeting various inflammatory and pain-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 31112-92-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,1,1 and 2 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 31112-92:
(7*3)+(6*1)+(5*1)+(4*1)+(3*2)+(2*9)+(1*2)=62
62 % 10 = 2
So 31112-92-2 is a valid CAS Registry Number.
31112-92-2Relevant academic research and scientific papers
Design and synthesis of quinolin-2(1H)-one derivatives as potent CDK5 inhibitors
Zhong, Wenge,Liu, Hu,Kaller, Matthew R.,Henley, Charles,Magal, Ella,Nguyen, Thomas,Osslund, Timothy D.,Powers, David,Rzasa, Robert M.,Wang, Hui-Ling,Wang, Weiya,Xiong, Xiaoling,Zhang, Jiandong,Norman, Mark H.
, p. 5384 - 5389 (2008/02/13)
Cyclin-dependent kinase 5 (CDK5) is a serine/threonine protein kinase and its deregulation is implicated in a number of neurodegenerative disorders such as Alzheimer's disease, amyotrophic lateral sclerosis, and ischemic stroke. Using active site homology modeling between CDK5 and CDK2, we explored several different chemical series of potent CDK5 inhibitors. In this report, we describe the design, synthesis, and CDK5 inhibitory activities of quinolin-2(1H)-one derivatives.
