31123-05-4 Usage
Uses
Used in Pharmaceutical Industry:
3,4-BIS-BENZYLOXY-BENZALDEHYDE OXIME is used as an organic intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Agrochemical Industry:
3,4-BIS-BENZYLOXY-BENZALDEHYDE OXIME is used as an organic intermediate in the synthesis of agrochemicals, aiding in the production of pesticides and other agricultural chemicals.
Used in Organic Compounds Synthesis:
3,4-BIS-BENZYLOXY-BENZALDEHYDE OXIME is used as a chelating agent in various chemical processes, facilitating the synthesis of different organic compounds.
Used in Chemical Research:
3,4-BIS-BENZYLOXY-BENZALDEHYDE OXIME is used as a reagent in organic reactions, particularly in the preparation of nitrogen-containing compounds, contributing to the advancement of chemical research.
Used in Material Development:
3,4-BIS-BENZYLOXY-BENZALDEHYDE OXIME has been studied for its potential applications in the development of new materials, indicating its versatility in various industrial applications.
Used in Antimicrobial Applications:
3,4-BIS-BENZYLOXY-BENZALDEHYDE OXIME has been studied for its antimicrobial properties, suggesting its potential use in applications requiring microbial control.
Used in Antioxidant Applications:
3,4-BIS-BENZYLOXY-BENZALDEHYDE OXIME has been studied for its antioxidant properties, indicating its potential use in applications requiring protection against oxidative damage.
Check Digit Verification of cas no
The CAS Registry Mumber 31123-05-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,1,2 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 31123-05:
(7*3)+(6*1)+(5*1)+(4*2)+(3*3)+(2*0)+(1*5)=54
54 % 10 = 4
So 31123-05-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H19NO3/c23-22-14-19-11-12-20(24-15-17-7-3-1-4-8-17)21(13-19)25-16-18-9-5-2-6-10-18/h1-14,23H,15-16H2/b22-14+
31123-05-4Relevant academic research and scientific papers
Design and synthesis of neolamellarin a derivatives targeting heat shock protein 90
Jiang, Long,Yin, Ruijuan,Wang, Xueting,Dai, Jiajia,Li, Jing,Jiang, Tao,Yu, Rilei
, p. 24 - 33 (2017/04/21)
In this study, we designed and synthesized a novel family of neolamellarin A derivatives that showed high inhibitory activity toward heat shock protein 90 (Hsp90), a kinase associated with cell proliferation. The 3,4-bis(catechol)pyrrole scaffold and the benzyl group with methoxy modification at N position of pyrrole are essential to the Hsp90 inhibitory activity and cytotoxicity of these compounds. Western blot analysis demonstrated that these compounds induced dramatic depletion of the examined client proteins of Hsp90, and accelerated cancer cell apoptosis. Docking simulations suggested that the binding mode of 9p was similar to that of the VER49009, a potent inhibitor of Hsp90. Further molecular dynamics simulation indicated that the hydrophobic interactions as well as the hydrogen bonds contributed to the high affinity of 9p to Hsp90.
INHIBITORS OF PHOSPHODIESTERASE TYPE-IV
-
Page/Page column 50, (2008/06/13)
The present invention relates to isoxazoline derivatives, which can be used as selective inhibitors of phosphodiesterase (PDE) type IV. In particular, compounds disclosed herein can be useful in the treatment of AIDS, asthma, arthritis, bronchitis, chronic obstructive pulmonary disease (COPD), psoriasis, allergic rhinitis, shock, atopic dermatitis, Crohn's disease, adult respiratory distress syndrome (ARDS), eosinophilic granuloma, allergic conjunctivitis, osteoarthritis, ulcerative colitis and other inflammatory diseases in a patient, particularly in humans. The present invention also relates to processes for the preparation of disclosed compounds, as well as pharmaceutical compositions thereof, and their use as phosphodiesterase (PDE) type IV inhibitors.
