311799-68-5Relevant academic research and scientific papers
Discovery of a Potent Inhibitor Class with High Selectivity toward Clostridial Collagenases
Sch?nauer, Esther,Kany, Andreas M.,Haupenthal, J?rg,Hüsecken, Kristina,Hoppe, Isabel J.,Voos, Katrin,Yahiaoui, Samir,Els?sser, Brigitta,Ducho, Christian,Brandstetter, Hans,Hartmann, Rolf W.
, p. 12696 - 12703 (2017)
Secreted virulence factors like bacterial collagenases are conceptually attractive targets for fighting microbial infections. However, previous attempts to develop potent compounds against these metalloproteases failed to achieve selectivity against human
