311804-01-0

Upstream product

• 311804-00-9 tert-butyl (S)-4-(furan-2-yl)-3-(hydroxymethyl)butanoate 
• 98-59-9 p-toluenesulfonyl chloride 
• 935-13-7 3-(2-furyl)propanoic acid 
• 10031-90-0 ethyl 3-(furan-2-yl)propanoate 
• 311803-98-2 (S)-3-Furan-2-ylmethyl-4-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-4-oxo-butyric acid tert-butyl ester 
• 311803-97-1 (4R,5S)-3-(3-Furan-2-yl-propionyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 311803-99-3 (S)-4-(tert-butoxy)-2-(furan-2-ylmethyl)-4-oxobutanoic acid 

Relevant academic research and scientific papers

Heteroaromatic side-chain analogs of pregabalin

A series of heteroaromatic analogs of pregabalin has been identified that possess anticonvulsant activity in the DBA/2 mouse model. The methods of synthesis and preliminary pharmacology are discussed herein.

3-heteroarylalkyl substituted gaba analogs

The invention is a novel series of compounds which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.