935-13-7Relevant articles and documents
Furan-PNA: A mildly inducible irreversible interstrand crosslinking system targeting single and double stranded DNA
Manicardi,Gyssels,Corradini,Madder
, p. 6930 - 6933 (2016)
We here report on the design and synthesis of tailor-made furan-modified peptide nucleic acid (PNA) probes for covalent targeting of single stranded DNA through a crosslinking strategy. After introducing furan-containing building blocks into a PNA sequence, hybridization and furan-oxidation based crosslinking to DNA is investigated. The structure of the crosslinked products is characterized and preliminary investigations concerning the application of these systems to double stranded DNA are shown.
Metal-Free Chemoselective Oxidative Dehomologation or Direct Oxidation of Alcohols: Implication for Biomass Conversion
Kim, Sun Min,Shin, Hun Yi,Kim, Dong Wan,Yang, Jung Woon
, p. 241 - 245 (2016/02/27)
A transition metal-free, chemoselective reaction was performed using the sodium tert-butoxide-oxygen (NaOtBu-O2) system, resulting in either oxidative dehomologation or direct oxidation of alcohols. In particular, the newly developed protocol may be used to predict the major product formed, which depends on alkyl chain length of the alcohols and reaction conditions. The rational mechanism of this transformation was also demonstrated by performing an 18O isotopic labelling experiment. This protocol presents a straightforward method for biomass conversion of a lignin model compound to phenol and benzoic acid.
Raney nickel-catalyzed hydrogenation of unsaturated carboxylic acids with sodium borohydride in water
Rao, Gopal Krishna,Gowda, Narendra B.,Ramakrishna, Ramesha A.
experimental part, p. 893 - 904 (2012/02/01)
A mild, selective, and green method for the reduction of unsaturated carboxylic acids with sodium borohydride-Raney nickel (W6) system in water is reported. This method is practical and safe and avoids use of organic solvents. Taylor & Francis Group, LLC.