3120-06-7

Usage

Classification

Pyrrole-2,5-dione derivative

Physical form

Yellow crystalline solid

Solubility

Sparingly soluble in water, more soluble in organic solvents

Uses

Building block for the synthesis of various organic compounds, production of pharmaceuticals and dyes, chemical intermediate in the synthesis of other organic compounds.

Upstream product

• 14156-13-9 3-ethylfuran-2,5-dione 
• 62-53-3 aniline 
• 64448-06-2 (N-phenyliminovinylidene)triphenylphosphorane 
• 600-18-0 2-Oxobutyric acid 

Relevant academic research and scientific papers

Cumulated Ylides, XVII. Synthesis of Cyclic Compounds from Triphenylphosphorane and Oxocarboxylic Acids - A Novel Method for Anellation

By entropically supported intramolecular Wittig reaction from α-keto carboxylic acids 23 with triphenylphosphorane (1) N-phenylmaleinisoimides 26 and -imides 29 are formed.The compounds 26 can be rearranged into 29 with a catalytic amount of sodium azide. - From γ-keto carboxylic acids 30 3-substituted 2-cyclopenten-1-ones 37 can be derived via the 3,6-dioxo-2-(triphenylphosphoranylidene)alkananilides 33.Analogously, 3-substituted 2-cyclohexen-1-ones 49 are formed from δ-keto carboxylic acids 46. o-Acylbenzoic acids 38, in the case R = H, are converted with 1 into the benzazepinedione derivative 44, and in the case R unlike H into 3-substituted 1-oxo-1H-indene-2-carboxanilides 45. - Starting from oxo carboxylic acids, possessing the carbonyl function in a ring, five- and six-membered rings can be anellated in a simple way.