3120-52-3

Usage

Uses

Used in Antiviral Applications:
6-Amino-2,3-dihydro-1,3-dimethyl-2-thioxopyrimidin-4(1H)-one is utilized as an antiviral agent for its inhibitory effects on viral replication. It has shown promise in the treatment of specific viral infections, making it a valuable compound in the development of new antiviral drugs.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 6-Amino-2,3-dihydro-1,3-dimethyl-2-thioxopyrimidin-4(1H)-one is used as a key component in the development of new drugs for various medical applications. Its unique structure and properties contribute to the creation of innovative therapeutic agents that address unmet medical needs.
Used in Medicinal Chemistry Research:
6-Amino-2,3-dihydro-1,3-dimethyl-2-thioxopyrimidin-4(1H)-one serves as a subject of interest in medicinal chemistry research. Scientists and researchers explore its potential applications, mechanisms of action, and interactions with biological targets to enhance understanding and facilitate the development of novel therapeutic agents.

InChI:InChI=1/C6H9N3OS/c1-8-4(7)3-5(10)9(2)6(8)11/h3H,7H2,1-2H3

Upstream product

• 372-09-8 cyanoacetic acid 
• 534-13-4 N,N-dimethylthiourea 
• 1027454-59-6 1-(2-Cyano-acetyl)-1,3-dimethyl-thiourea 

Downstream Products

• 6501-95-7 6-amino-1,3-dimethyl-5-nitroso-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 
• 6501-96-8 1,3-dimethyl-5,6-diamino-2-thiouracil 
• 96996-36-0 1,3,7-Trimethyl-5-(3-nitro-phenyl)-4-oxo-2-thioxo-1,2,3,4,5,8-hexahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid methyl ester 
• 96995-99-2 5-(2,3-Dichloro-phenyl)-1,3,7-trimethyl-4-oxo-2-thioxo-1,2,3,4,5,8-hexahydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid 2-(benzyl-methyl-amino)-ethyl ester 

Relevant academic research and scientific papers

Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation

The increased levels of cyclic nucleotides (cGMP and cAMP) in enterocytes trigger intracellular mechanisms of ion and fluid secretion into the lumen, causing secretory diarrhea. Twelve novel pyridopyrimidines derived from 5-(3,5-bistrifluoromethylphenyl)-

NEW PYRIDOPYRIMIDINES DERIVATIVES COMPOUNDS

The present invention describes new pyridopyrimidine derivatives compounds with structure represented by General Formula (I): or pharmaceutically acceptable salts thereof, or their mixtures (in any ratio), a pharmaceutical composition containing them, a method for using the new pyridopyrimidine derivatives compounds as inhibitor of the cyclic nucleotide synthesis or as inhibitor of the cAMP and cGMP synthesis, and their uses in the prophylactic and/or curative treatment of diarrhea, colitis and irritable bowel syndrome.

Structure-Activity Relationships of 1,3-Dialkylxanthine Derivatives at Rat A3 Adenosine Receptors

1,3-Dialkylxanthine analogues containing carboxylic acid and other charged groups on 8-position substituents were synthesized.These derivatives were examined for affinity in radioligand binding assays at rat brain A3 adenosine receptors stably