6501-95-7Relevant academic research and scientific papers
Complexes with 6-amino-5-nitroso-2-thiouracil and violuric acid derivatives containing the fac-ReI(CO)3 core: Synthesis, XRD structural and photoluminescence characterization
Illán-Cabeza, Nuria A.,García-García, Antonio R.,Moreno-Carretero, Miguel N.
experimental part, p. 262 - 267 (2011/04/12)
The fac-tricarbonylrhenium(I) complexes of the 6-amino-1,3-dimethyl-5- nitroso-2-thiouracil (DANTU) and violuric acid (VIO) and its mono- (MVIO) and dimethyl (DVIO) derivatives have been prepared. The complexes have been characterized by elemental analysis, IR, 1H and 13C NMR spectral methods and luminescence spectroscopy. The structures of [ReCl(CO) 3(DANTU)], [Re(H2O)(CO)3(VIOH-1)] and [Re(H2O)(CO)3(DVIOH-1)] complexes were solved from single-crystal X-ray diffraction experiments. The coordination environment around the Re(I) may be described as a distorted octahedron in which the ligand behaves in a bidentate fashion through the nitrogen atom of the nitroso group and an adjacent carbonylic oxygen, making a five-membered chelate ring. The coordination sphere is completed with three carbonyl groups in fac-arrangement and one chlorine atom (DANTU complex) or water molecule (VIO complexes). The higher acidity of violuric acids, if compared with DANTU one, may explain both synergic deprotonation and chloride substitution in the [ReCl(CO)3]+ moiety to form the Re-violurato complexes.
Structure-Activity Relationships of 1,3-Dialkylxanthine Derivatives at Rat A3 Adenosine Receptors
Kim, Hea Ok,Ji, Xiao-duo,Melman, Neli,Olah, Mark E.,Stiles, Gary L.,Jacobson, Kenneth A.
, p. 3373 - 3382 (2007/10/02)
1,3-Dialkylxanthine analogues containing carboxylic acid and other charged groups on 8-position substituents were synthesized.These derivatives were examined for affinity in radioligand binding assays at rat brain A3 adenosine receptors stably
