312299-66-4

Basic information

• Product Name: Phenol, 3,4,5-trimethoxy-, 4-methylbenzenesulfonate
• CAS NO: 312299-66-4
• Molecular Formula: C16H18O6S
• Molecular Weight: 338.381
• Mol File: 312299-66-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phenol, 3,4,5-trimethoxy-, 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 3,4,5-trimethoxy-, 4-methylbenzenesulfonate(312299-66-4)
• EPA Substance Registry System: Phenol, 3,4,5-trimethoxy-, 4-methylbenzenesulfonate(312299-66-4)

Safety Data

• Hazardous Substances Data: 312299-66-4(Hazardous Substances Data)

Upstream product

• 642-71-7 3,4,5-trimethoxyphenol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 6443-69-2 3,4,5-trimethoxytoluene 
• 1262526-19-1 2-(3,4,5-trimethoxyphenyl)quinoxaline 1-oxide 
• 1262526-16-8 2-(3,4,5-trimethoxyphenyl)quinoline 1-oxide 
• 1262526-15-7 2-(3,4,5-trimethoxyphenyl)pyrazine 1-oxide 
• 1262526-08-8 6-(3,4,5-trimethylphenyl)pyridazine 1-oxide 
• 1126639-50-6 4-n-butyl-5-(3,4,5-trimethoxyphenyl)-1-(3-methylphenyl)-1H-1,2,3-triazole 
• 1019107-63-1 5-phenyl-2-(3,4,5-trimethoxyphenyl)oxazole 

Relevant articles and documents

Nickel-catalyzed methylation of aryl halides/tosylates with methyl tosylate

This work describes the cross-electrophile methylation of aryl bromides and aryl tosylates with methyl tosylate. The mild reaction conditions allow effective methylation of a wide set of heteroaryl electrophiles and dimethylation of dibromoarenes.

Novel sulfonate analogues of combretastatin A-4: Potent antimitotic agents

Sulfonate analogues of combretastatin A-4 have been prepared. These compounds compete with colchicine and combretastatin A-4 for the colchicine binding site on tubulin and are potent inhibitors of tubulin polymerization and cell proliferation. Importantly, these compounds also inhibit the proliferation of P-glycoprotein positive (+) cancer cells, which are resistant to many other antitumor agents.