3123-22-6Relevant articles and documents
Cycloadditions of cyclohexynes and cyclopentyne
Medina, Jose M.,McMahon, Travis C.,Jimnez-Oss, Gonzalo,Houk,Garg, Neil K.
, p. 14706 - 14709 (2014)
We report the strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds. Experimental and computational studies of a 3-substituted cyclohexyne are also described. The observed regioselectivities are explained by the distortion/interaction model.