312325-75-0

Basic information

• Product Name: 2-Pyridinecarboxylicacid,6-(cyanomethyl)-(9CI)
• Synonyms: 2-Pyridinecarboxylicacid,6-(cyanomethyl)-(9CI);6-(cyanomethyl)picolinic acid;6-(CYANOMETHYL)PYRIDINE-2-CARBOXYLIC ACID
• CAS NO: 312325-75-0
• Molecular Formula: C8H6N2O2
• Molecular Weight: 162.14544
• Product Categories: GLYCINESCAFFOLD
• Mol File: 312325-75-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinecarboxylicacid,6-(cyanomethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxylicacid,6-(cyanomethyl)-(9CI)(312325-75-0)
• EPA Substance Registry System: 2-Pyridinecarboxylicacid,6-(cyanomethyl)-(9CI)(312325-75-0)

Safety Data

• Hazardous Substances Data: 312325-75-0(Hazardous Substances Data)

Upstream product

• 21190-87-4 6-bromo-pyridine-2-carboxylic acid 
• 75-05-8 acetonitrile 

Downstream Products

• 1000525-37-0 methyl 6-(cyanomethyl)pyridine-2-carboxylate 
• 1433826-03-9 1-benzyl 2-methyl 6-(2-(tert-butoxycarbonylamino)ethyl)piperidine-1,2-dicarboxylate 

Relevant articles and documents

NOVEL FERROPORTIN INHIBITORS

The invention relates to novel ferroportin inhibitors of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.

BICYCLIC AZA-AMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS

The present invention relates to compounds of formula (I) having a bicyclic aza-amides scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said bicyclic aza- amides compounds can be used for prophylaxis and/or treatment of psychiatric disorders and neurodegenerative diseases, disorders and conditions.

Facile cyanomethylation of bromopyridines by nucleophilic substitution with lithioacetonitrile

Substituted bromopyridines undergo facile nucleophilic substitution with lithioacetonitrile under mild conditions to afford the corresponding cyanomethylated products.