312329-73-0Relevant academic research and scientific papers
Au(I)-Catalyzed Oxidative Functionalization of Yndiamides
Tong, Zixuan,Garry, Olivia L.,Smith, Philip J.,Jiang, Yubo,Mansfield, Steven J.,Anderson, Edward A.
supporting information, p. 4888 - 4892 (2021/06/28)
Yndiamides, underexplored cousins of ynamides, offer rich synthetic potential as doubly nitrogenated two carbon building blocks. Here we report a gold-catalyzed oxidative functionalization of yndiamides to access unnatural amino acid derivatives, using a wide range of nucleophiles as a source of the amino acid side chain. The transformation proceeds under mild conditions, is highly functional group tolerant, and displays excellent regioselectivity through subtle steric differentiation of the yndiamide nitrogen atom substituents.
Synthesis of ynamides from formamides
Brückner, David
, p. 3809 - 3814 (2007/10/03)
N-Formyl-tosylamides can be efficiently converted to N-ethynyl-tosylamides in two steps via the corresponding dichlorovinylamides.
Synthesis of ynamides and ynol ethers via formamides and formates
Bruckner
, p. 1402 - 1404 (2007/10/03)
The efficient conversion of N-formyl-tosylamides to N-ethynyl-tosylamides via the corresponding dichlorovinylamides is described. Furthermore syntheses of N-formyl-tosylamides are reported.
