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Usage

Uses

Used in Automotive and Industrial Lubricants:
1H-Benzotriazole-1-carboxaldehyde is used as a corrosion inhibitor for protecting metals from corrosion in automotive fluids and industrial lubricants, thereby extending the life of machinery and equipment.
Used in Polymer Chemistry:
1H-Benzotriazole-1-carboxaldehyde is used as a photoinitiator in polymer chemistry, facilitating the curing process of polymers under UV light, which is crucial for the manufacturing of various products.
Used in Plastics and Coatings:
1H-Benzotriazole-1-carboxaldehyde is used as a UV stabilizer in plastics and coatings to protect them from degradation caused by exposure to sunlight, ensuring their durability and longevity.
Used in Pharmaceutical Production:
1H-Benzotriazole-1-carboxaldehyde is used as an intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs and medications.
Used in Dye and Optical Brightener Manufacturing:
1H-Benzotriazole-1-carboxaldehyde is used in the production of dyes and optical brighteners, enhancing the color and brightness of textiles, paper, and other materials.
It is important to handle 1H-Benzotriazole-1-carboxaldehyde with care, as it can be harmful if ingested, inhaled, or comes into contact with the skin. Proper safety measures should be taken during its use and storage to minimize potential risks.

InChI:InChI=1/C7H5N3O/c11-5-10-7-4-2-1-3-6(7)8-9-10/h1-5H

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 64-18-6 formic acid 
• 2258-42-6 formyl acetic anhydride 
• 1558-67-4 formic anhydride 
• 2565-30-2 formyl chloride 

Downstream Products

• 16135-31-2 p-nitroformanilide 
• 7418-32-8 N-(2-nitrophenyl)formamide 
• 61949-23-3 menthyl formate 
• 617-84-5 N-formyldiethylamine 
• 103-70-8 Formanilid 
• 6343-54-0 N-benzylformamide 
• 1988-18-7 naphthalen-2-yl formate 
• 104-57-4 benzyl formate 
• 592-84-7 n-butyl formate 
• 312329-75-2 N-allyl-N-formyl-4-methyl-benzenesulfonamide 
• 312329-73-0 N-butyl-N-formyl-4-methyl-benzenesulfonamide 
• 312329-77-4 N-benzyl-N-formyl-4-methyl-benzenesulfonamide 
• 312329-74-1 N-Formyl-N-isopropyl-4-methyl-benzenesulfonamide 
• 607715-22-0 2-[3-(benzyloxy-formyl-amino)-2-methyl-propionylamino]-3,3,N,N-tetramethyl-butyramide 

Relevant academic research and scientific papers

Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

Herein we report a Ni-catalyzed reductive transamidation of conveniently available N-acyl benzotriazoles with alkyl, alkenyl, and aryl nitro compounds, which afforded various amides with good yields and a broad substrate scope. The same catalytic reaction conditions were also applicable for N-sulfonyl benzotriazoles, which could undergo smooth reductive coupling with nitroarenes and nitroalkanes to afford the corresponding sulfonamides.

Tris(trimethylsilyl) phosphite as key synthon for convenient synthesis of new organosilicon(phosphorus)-containing N-heterocycles

The new functionalized hydroxymethylphosphonic and methylenediphosphonic acids are synthesized via unique reaction of tris(trimethylsilyl) phosphite and N-formyl N-heterocycles, N-substituted 4-piperidones, 3-quinuclidone, and 2-adamantanone at the presence of effective catalyst – trimethylsilyl triflate under mild conditions.

Synthesis of new functionalized mono- and diphosphonic acids with five-membered aza-heterocycles moieties

The new functionalized hydroxymethylphosphonic and methylenediphosphonic acids are synthesized via unique reaction of tris(trimethylsilyl)phosphite and N-formyl derivatives of five-membered aza-heterocycles at the presence of effective catalyst—trimethylsilyl triflate.

Synthesis of new five-membered N-heterocycle derivatives of mono- and bis-phosphonic acids

The new functionalized hydroxymethylphosphonic and methylenebis(phosphonic) acids are synthesized via reaction of tris(trimethylsilyl) phosphite and N-formyl derivatives of five-membered N-heterocycles in the presence of trimethylsilyl triflate.

New functionalized derivatives of mono- and diphosphonic acids substituted with five-membered nitrogen heterocycles

New types of (hydroxymethyl)phosphonic and (methylene)diphosphonic acids bearing heterocyclic fragments were synthesized by addition of tris(trimethylsilyl) phosphite to N-formyl derivatives of five-membered nitrogen heterocycles.

Palladium-mediated [2+1] cycloaddition of norbornene derivatives with ynamides

An efficient palladium-catalyzed [2+1] cycloaddition between ynamides and norbornenes or norbornadienes is reported. Both phosphapalladacycles and palladium/secondary phosphine oxide catalytic systems were found to be competent for the transformation allowing the preparation of aminomethylenecyclopropanes. The reaction showed general applicability to various functionalized bicyclo[2.2.1]hept-2-enes and ynamides. A chiral phosphapalladacycle was tested to carry out this transformation in an enantioselective fashion.

Synthesis of 3-aza-bicyclo[3.1.0]hexan-2-one derivatives via gold-catalyzed oxidative cyclopropanation of N -allylynamides

N-Allylynamides with various functional groups and different substitution patterns can be converted into 3-aza-bicyclo[3.1.0]hexan-2-one derivatives in moderate to high yield using IMesAuCl/AgBF4 as the catalyst and pyridine N-oxide as the oxidant. A noncarbene mediated approach is proposed as the mechanism.

Fast, economic, and green synthesis of N-formylated benzotriazoles

Formylation is an integral part of organic, medicinal, and biological chemistry both in industrial and academic set-ups. A reflection of this importance is the number of approaches and reagents that have been developed to achieve it. We have developed a fast, efficient, and environmentally friendly procedure for the synthesis of N-formylated benzotriazoles.