31236-61-0

Upstream product

• 931-57-7 1-methoxy-cyclohex-1-ene 
• 30830-47-8 benzyl N-chlorocarbamate 
• 92645-06-2 2-cyclohexanol 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 286-20-4 cyclohexane-1,2-epoxide 
• 6850-38-0 2-aminocyclohexanol 
• 31236-57-4 (2,2-Dimethoxy-cyclohexyl)-carbamic acid benzyl ester 

Downstream Products

• 17578-82-4 N-(2-oxocyclohexyl)acetamide 
• 123719-55-1 (1R*,2S*)-(+/-)--1-ethenyl-1-cyclohexanol 
• 123719-55-1 (1S*,2S*)-(+/-)-2--1-ethenyl-1-cyclohexanol 
• 123719-63-1 (3aS,7aR)-7a-Vinyl-hexahydro-benzooxazol-2-one 
• 123719-63-1 (3aR,7aR)-7a-Vinyl-hexahydro-benzooxazol-2-one 
• 143817-95-2 (2R*,8aS*)-1-(benzyloxycarbonyl-2-methoxycarbonyl)-1,2,3,5,6,7,8,8a-octahydroquinoline 
• 143817-95-2 (2S*,8aS*)-1-(benzyloxycarbonyl-2-methoxycarbonyl)-1,2,3,5,6,7,8,8a-octahydroquinoline 
• 123719-58-4 C₂₄H₃₅NO₄Si 
• 123719-58-4 C₂₄H₃₅NO₄Si 
• 143818-06-8 (1S*,2S*)-amino>-1-ethenyl-1-cyclohexanol 
• 143818-06-8 (1R*,2S*)-amino>-1-ethenyl-1-cyclohexanol 
• 123719-57-3 (4aS*,8aS*)-4-(benzyloxycarbonyl)-8a-ethenyl-2-oxo-3,4,4a,5,6,7,8,8a-octahydro-2H-1,4-benzoxazine 
• 123719-57-3 (4aS*,8aR*)-4-(benzyloxycarbonyl)-8a-ethenyl-2-oxo-3,4,4a,5,6,7,8,8a-octahydro-2H-1,4-benzoxazine 
• 123719-49-3 (2S,8aR)-3,5,6,7,8,8a-Hexahydro-2H-quinoline-1,2-dicarboxylic acid 1-benzyl ester 

Relevant academic research and scientific papers

Carbazole-Containing Sulfonamides as Cryptochrome Modulators

The subject matter herein is directed to carbazole-containing sulfonamide derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula I wherein the variable R1, R2, R3, R4, R5, R6, R7, A, B, C, D, E, F, G, H, a, and b are accordingly described. Also provided are pharmaceutical compositions comprising the compounds of formula I to treat a Cry-mediated disease or disorder, such as diabetes, obesity, metabolic syndrome, Cushing's syndrome, and glaucoma.

An Efficient Stereoselective Synthesis of Δ4,5-Pipecolic Esters

The synthesis of racemic and enantiomerically homogeneous pipecolic esters from 1-amino-3-buten-2-ols is reported.The synthesis of enantiomerically homogeneous N-methylpipecolic esters requires four chemical steps from N-t-BOC-protected amino esters.The key step of the sequence is a conformationally restricted Claisen rearrangement.The method affords complete control of the absolute and relative stereochemistry of all three stereogenic centers in pipecolic ester 22 which is obtained in 33percent overall yield from N-t-BOC-L-alanine ethyl ester 16a.

STEREOSELECTIVE SYNTHESIS OF SUBSTITUTED PIPECOLIC ACIDS

The stereoselective synthesis of Δ4,5-pipecolic acid derivatives is described.The key step in the sequence is a sigmatropic rearrangement.