31264-51-4Relevant academic research and scientific papers
Selectivity in alkylation of phenols with 1-bromo-3-chloropropane using phase-transfer catalysis
Reinholz,Becker,Hagenbruch,Schafer,Schmitt
, p. 1069 - 1071 (2007/10/02)
The use of various phase-transfer catalysts in the alkylation of phenol and substituted phenols with 1-bromo-3-chloropropane was investigated. When a quarternary ammonium salt of the general formula R'4N+ X-, where R' = alkyl with a minimum chain length of 4 was used, a mixture of 1-aryloxy-3-chloropropane and 1-aryloxy-3-bromopropane resulted. The effect of counterion, added potassium bromide, and catalysts other than quarternary ammonium salts were assessed for the halopropylation of 2,5-dimethylphenol.
