312693-52-0

Usage

Uses

Used in Pharmaceutical Industry:
(E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is used as a building block for the synthesis of complex organic molecules, particularly in the development of new pharmaceuticals. Its ability to form carbon-carbon bonds through cross-coupling reactions allows for the creation of diverse molecular structures with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, (E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is used as a key intermediate in the synthesis of various agrochemicals, such as pesticides and herbicides. Its reactivity and versatility in forming carbon-carbon bonds contribute to the development of novel and effective compounds for agricultural use.
Used in Organic Chemistry Research:
(E)-1-HEXENE-1,2-DIBORONIC ACID BIS(PINACOL) ESTER is also used as a research tool in the field of organic chemistry. Its unique reactivity and stability make it an attractive candidate for studying new reaction mechanisms and exploring the synthesis of novel organic compounds.

Upstream product

• 693-02-7 hex-1-yne 
• 73183-34-3 bis(pinacol)diborane 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 

Downstream Products

• 1519954-08-5 methyl 4-(4-methylphenyl)-2-(morpholino)oct-3-enoate 
• 1519954-09-6 methyl 4-(2-methylphenyl)-2-(morpholino)oct-3-enoate 
• 1519954-12-1 methyl 2-dibenzylamino-4-(4-methylphenyl)oct-3-enoate 
• 1519954-15-4 methyl 4-(4-nitrophenyl)-2-(pyridin-4-yl)piperazinooct-3-enoate 
• 1519954-17-6 methyl 4-(4-methoxyphenyl)-2-[4-(1,1-dimethylethoxy)carbonyl]-piperazinooct-3-enoate 
• 1519953-88-8 methyl 2-dibenzylamino-4-(4,4,4,5-tetramethyl-1,3,2-dioxaborolan-2-yl)oct-3-enoate 

Relevant academic research and scientific papers

Hydroboration of Terminal Alkenes and trans-1,2-Diboration of Terminal Alkynes Catalyzed by a Manganese(I) Alkyl Complex

A MnI-catalyzed hydroboration of terminal alkenes and a 1,2-diboration of terminal alkynes with pinacolborane (HBPin) is described. For alkenes, anti-Markovnikov hydroboration takes place; for alkynes the reaction proceeds with excellent trans-1,2-selectivity. The most active pre-catalyst is bench-stable alkyl bisphosphine MnI complex fac-[Mn(dippe)(CO)3(CH2CH2CH3)]. The catalytic process is initiated by migratory insertion of a CO ligand into the Mn–alkyl bond to yield an acyl intermediate, which undergoes B?H bond cleavage of HBPin (for alkenes) and rapid C?H bond cleavage (for alkynes), forming the active MnI boryl and acetylide catalysts [Mn(dippe)(CO)2(BPin)] and [Mn(dippe)(CO)2(C≡CR)], respectively. A broad variety of aromatic and aliphatic alkenes and alkynes was efficiently and selectively borylated. Mechanistic insights are provided based on experimental data and DFT calculations revealing that an acceptorless reaction is operating involving dihydrogen release.

Regio- and stereocontrolled access to ?-boronated unsaturated amino esters and derivatives from (z)-alkenyl 1,2-bis(boronates)

The Borono-Mannich reaction of (Z)-1-alkene-1,2-diboronic esters proceeded regioselectively at the terminal C-B bond to afford (E)-?-boronated unsaturated amino esters in good yields. These compounds were then subjected to Suzuki couplings for the creatio