31270-80-1

Basic information

• Product Name: 4-CHLOROFURO[3,2-C]PYRIDINE
• Synonyms: SALOR-INT L299537-1EA;4-CHLOROFURO[3,2-C]PYRIDINE;4-CHLOROFURO[3,2-]PYRIDINE;4-Chlorofuro[3,2-c]pyridine, 95+%;1. 4-Chlorofuro[3,2-C]Pyridine;4-Chlorofuro[3,2-c]pyridine HCl;4-Chloro-5-azabenzo[b]furan, 4-Chloro-5-aza-1-benzofuran
• CAS NO: 31270-80-1
• Molecular Formula: C₇H₄ClNO
• Molecular Weight: 153.57
• EINECS: -0
• Product Categories: Heterocycles series;Halides;Fused Ring Systems
• Mol File: 31270-80-1.mol
• Article Data: 13

Chemical Properties

• Melting Point: 41 °C
• Boiling Point: 243℃
• Flash Point: 101℃
• Appearance: Yellow powder
• Density: 1.377
• Vapor Pressure: 0.052mmHg at 25°C
• Refractive Index: 1.624
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.69±0.30(Predicted)
• CAS DataBase Reference: 4-CHLOROFURO[3,2-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROFURO[3,2-C]PYRIDINE(31270-80-1)
• EPA Substance Registry System: 4-CHLOROFURO[3,2-C]PYRIDINE(31270-80-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 31270-80-1(Hazardous Substances Data)

Usage

General Description

4-CHLOROFURO[3,2-C]PYRIDINE is a chemical compound with the molecular formula C7H4ClNO. It is a heterocyclic aromatic compound that contains a furan ring fused to a pyridine ring, with a chlorine atom attached to the furan ring. 4-CHLOROFURO[3,2-C]PYRIDINE is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential biological and pharmacological activities, including as an antiviral, antifungal, and antibacterial agent. Additionally, 4-CHLOROFURO[3,2-C]PYRIDINE has been investigated for its potential as a fluorescent probe for detecting biological molecules and as a precursor for creating functional materials in organic electronics.

InChI:InChI=1/C7H4ClNO/c8-7-5-2-4-10-6(5)1-3-9-7/h1-4H

Upstream product

• 26956-43-4 furo[3,2-c]pyridine-4-ol 
• 98-01-1 furfural 
• 119924-26-4 (E)-3-(2-furanyl)-2-propenoyl azide 
• 33007-15-7 7-hydroxy-6,7-dihydro-5H-furo[3,2-c]pyridin-4-one 
• 46265-05-8 2-(2-amino-1-hydroxy-ethyl)-furan-3-carboxylic acid ethyl ester 
• 539-47-9 3-(fur-2-yl)crotonic acid 
• 20689-54-7 3-furanylacryloyl chloride 
• 29080-01-1 β-(2-Furan)-vinylisocyanat 
• 539-47-9 3-(2-furyl)acrylic acid 
• 59898-36-1 (E)-3-Furan-2-yl-acryloyl azide 
• 57420-06-1 furo<3,2-c>pyridine N-oxide 
• 26956-43-4 5H-furo[3,2-c]pyridin-4-one 

Downstream Products

• 46802-94-2 benzyl-furo[3,2-c]pyridin-4-yl-amine 
• 271-92-1 furo[3,2-c]pyridine 
• 86518-10-7 acetyl-2 chloro-4 furo<3,2-c>pyridine 
• 63618-60-0 methoxy-4 furo<3,2-c>pyridine 
• 76311-99-4 4-phenylfuro<3,2-c>pyridine 
• 26956-43-4 furo[3,2-c]pyridine-4-ol 
• 1125865-26-0 N-((7,8-difluoro-2-methoxyquinolin-4-yl)methyl)-N-phenylfuro[3,2-c]pyridin-4-amine 
• 1613479-47-2 C₁₃H₇F₂NO₂ 
• 1609581-20-5 2-bromo-5-(furo[3,2-c]pyridin-4-yloxy)aniline 
• 1609581-18-1 1-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]propan-1-one 
• 1609577-20-9 2-(4,6-dimethylpyrimidin-5-yl)-5-(furo[3,2-c]pyridin-4-yloxy)benzonitrile 
• 1609577-18-5 4-{[4-(1-methyl-1H-pyrazol-5-yl)phenyl]sulfanyl}furo[3,2-c]pyridine trifluoroacetate salt 
• 1609581-86-3 4-[4-(3-hydrazinyl-5-methylpyridazin-4-yl)-3-methylphenoxy]furo[3,2-c]pyridine 
• 1609583-30-3 potassium trifluoro[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]borate 

Relevant articles and documents

Organic metal compound and organic light-emitting device

Organic metal compounds and organic light-emitting devices employing the same are provided. The organic metal compound has a chemical structure of Formula (I) or Formula (II): In particular, one of the following two conditions (1) and (2) is met: (1) R1 is deuterium or C1-6 deuterated alkyl group, when R3 and R4 are independently hydrogen, halogen, C1-6 alkyl group, C1-6 fluoroalkyl or C3-12 heteroaryl group; and (2) R1 is hydrogen, deuterium, C1-6 alkyl group, C1-6 deuterated alkyl group, C3-12 heteroaryl group, or C6-12 aryl group, when at least one of R3 and R4 is C6-12 aryl group or C6-12 fluoroaryl group.

Discovery of a 4-aryloxy-1H-pyrrolo[3,2-c]pyridine and a 1-aryloxyisoquinoline series of TRPA1 antagonists

A series of TRPA1 antagonists is described having a 4-aryloxy-1H-pyrrolo[3,2-c]pyridine or a 1-aryloxyisoquinoline scaffold. These compounds have high ligand efficiency and favorable physical properties and may thus serve as scaffolds for further optimization.

Design and synthesis of piperazinylpyridine derivatives as novel 5-HT 1A agonists/5-HT3 antagonists for the treatment of irritable bowel syndrome (IBS)

We have prepared a series of piperazinylpyridine derivatives for the treatment of irritable bowel syndrome (IBS). These compounds, which were designed by pharmacophore analysis, bind to both serotonin subtype 1A (5-HT 1A) and subtype 3 (5-HT3) receptors. The nitrogen atom of the isoquinoline, a methoxy group and piper-azine were essential to the pharmacophore for binding to these receptors. We also synthesized furo- and thienopyridine derivatives according to structure-activity relationship analyses. Compound 17c (TZB-20810) had high affinities to these receptors and exhibited 5-HT1A agonistic activity and 5-HT3 antagonistic activity concurrently, and is a promising drug for further development in the treatment of IBS.