312751-53-4 Usage
Uses
Used in Pharmaceutical Industry:
[2-(1H-INDOL-3-YL)-ETHYL]-THIOUREA is used as a pharmaceutical intermediate for its potential therapeutic properties. [2-(1H-INDOL-3-YL)-ETHYL]-THIOUREA's anti-inflammatory, analgesic, and antithyroid effects make it a valuable candidate for the development of new drugs targeting various health conditions.
Used in Chemical Synthesis:
In the chemical synthesis industry, [2-(1H-INDOL-3-YL)-ETHYL]-THIOUREA serves as a key building block for the creation of more complex molecules. Its unique structure, including the indole group, allows for the synthesis of a wide range of organic compounds with diverse applications.
Used in Drug Development Research:
[2-(1H-INDOL-3-YL)-ETHYL]-THIOUREA is employed as a research tool in drug development. Its potential therapeutic properties and the diverse pharmacological activities of indole derivatives make it an important compound for exploring new drug candidates and understanding their mechanisms of action.
Used in Organic Synthesis:
In the field of organic synthesis, [2-(1H-INDOL-3-YL)-ETHYL]-THIOUREA is utilized as a versatile reagent for the synthesis of various organic compounds. Its unique structure and functional groups enable the formation of a wide range of products with different applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 312751-53-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,7,5 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 312751-53:
(8*3)+(7*1)+(6*2)+(5*7)+(4*5)+(3*1)+(2*5)+(1*3)=114
114 % 10 = 4
So 312751-53-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3S/c12-11(15)13-6-5-8-7-14-10-4-2-1-3-9(8)10/h1-4,7,14H,5-6H2,(H3,12,13,15)
312751-53-4Relevant academic research and scientific papers
Five-membered heterocyclic compounds as inhibitors of SRC family protein kinase.
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Page/Page column 14, (2008/06/13)
The present invention refers to novel substituted aromatic heteroaryl derivatives of formula (I). with the definitions of A, L1, L2, G, J, X and Y according to claim 1. These novel compounds are useful for the inhibition of protein kinases, particularly of the inhibition of Src family protein kinases. Methods for inhibiting kinases by contacting kinases with these novel compounds are disclosed. In another embodiment the present invention refers to pharmaceutical compositions containing these novel compounds and their use for the preparation of medicaments for treating diseases or disorders associated with unphysiological activity of kinases in the body, particularly for the treatment of cancer, immunosuppression, and osteoporosis.
A convenient method for the preparation of primary and symmetrical N,N'-disubstituted thioureas
Herr,Kuhler,Meckler,Opalka
, p. 1569 - 1574 (2007/10/03)
A convenient process for the preparation of both primary thioureas 2 and symmetrical N,N'-disubstituted thioureas 6 based on the condensation of amine hydrohalides 5 with potassium thiocyanate has been developed. This approach tolerates sterically bulky primary amine substrates (both chiral and achiral), and the products can usually be isolated by a simple filtration of the reaction mixture. This method is an especially attractive alternative for the synthesis of thioureas when the corresponding isothiocyanates are unavailable, or difficult to prepare. It is also worth noting that a wide variety of amine hydrohalides, which are used in this procedure, are commercially available.
