312931-07-0

Downstream Products

• 1007578-70-2 5-{3-[(2-Chloroethyl)oxy]phenyl}-2-thiophenecarboxamide 
• 1007578-72-4 5-(3-Hydroxyphenyl)-2-thiophenecarboxamide 
• 1007578-71-3 ethyl 5-{3-[(2-oxoethyl)oxy]phenyl}-2-thiophenecarboxylate 
• 1007578-47-3 ethyl 5-(3-{[2,2-bis(ethyloxy)ethyl]oxy}phenyl)-2-thiophene carboxylate 

Relevant academic research and scientific papers

Metalloprotease inhibitors

Compounds of formula (I) and pharmaceutically-acceptable derivatives thereof, are matrix metalloprotease inhibitors, useful in treatment of conditions mediated by matrix metalloproteases, such as chronic dermal ulcers.

Composition for the treatment of damaged tissue

A pharmaceutical for use in damaged tissue, such as wound, treatment (e.g. healing) is described. The pharmaceutical comprising a composition which comprises: (a) a growth factor; and (b) an inhibitor agent; and optionally (c) a pharmaceutically acceptable carrier, diluent or excipient; wherein the inhibitor agent can inhibit the action of at least one specific adverse protein (e.g. a specific protease) that is upregulated in a damaged tissue, such as a wound, environment.