312936-89-3 Usage
Uses
Used in Pharmaceutical Industry:
2-Methoxy-4-(trifluoromethyl)-phenylboronic acid is used as a synthetic intermediate for the development of pharmaceutical compounds. Its ability to form carbon-carbon bonds through Suzuki coupling reactions makes it a valuable tool in the synthesis of complex organic molecules, including potential drug candidates.
Used in Chemical Research:
In the field of chemical research, 2-Methoxy-4-(trifluoromethyl)-phenylboronic acid serves as a reagent in various organic synthesis processes. Its involvement in cross-coupling reactions allows researchers to create new compounds with specific properties, contributing to the advancement of chemical knowledge and the discovery of novel materials.
Used in Material Science:
2-Methoxy-4-(trifluoromethyl)-phenylboronic acid is utilized in material science as a component in the synthesis of new materials with unique properties. Its role in forming carbon-carbon bonds can lead to the development of materials with improved characteristics for use in various applications, such as electronics, coatings, and polymers.
Used in Organic Synthesis:
As a key component in organic synthesis, 2-Methoxy-4-(trifluoromethyl)-phenylboronic acid is used as a building block for creating a wide range of organic compounds. Its versatility in forming carbon-carbon bonds through Suzuki coupling reactions makes it an essential tool for chemists looking to construct complex organic molecules for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 312936-89-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,9,3 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 312936-89:
(8*3)+(7*1)+(6*2)+(5*9)+(4*3)+(3*6)+(2*8)+(1*9)=143
143 % 10 = 3
So 312936-89-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H8BF3O3/c1-15-7-4-5(8(10,11)12)2-3-6(7)9(13)14/h2-4,13-14H,1H3
312936-89-3Relevant academic research and scientific papers
1-[(1-methyl-1 H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 positive allosteric modulators for the treatment of psychosis
Zhang, Lei,Brodney, Michael A.,Candler, John,Doran, Angela C.,Duplantier, Allen J.,Efremov, Ivan V.,Evrard, Edel,Kraus, Kenneth,Ganong, Alan H.,Haas, Jessica A.,Hanks, Ashley N.,Jenza, Keith,Lazzaro, John T.,Maklad, Noha,McCarthy, Sheryl A.,Qian, Weimin,Rogers, Bruce N.,Rottas, Melinda D.,Schmidt, Christopher J.,Siuciak, Judith A.,Tingley III, F. David,Zhang, Andy Q.
experimental part, p. 1724 - 1739 (2011/05/07)
A novel series of mGluR2 positive allosteric modulators (PAMs), 1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines, is herein disclosed. Structure-activity relationship studies led to potent, selective mGluR2 PAMs with excellent pharmacokinetic profiles. A representative lead compound (+)-17e demonstrated dose-dependent inhibition of methamphetamine-induced hyperactivity and mescaline-induced scratching in mice, providing support for potential efficacy in treating psychosis.
BENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR
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Page/Page column 70-71, (2010/11/30)
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
AZABENZIMIDAZOLYL COMPOUNDS
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Page/Page column 66, (2008/06/13)
Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I), as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
