312944-36-8

Basic information

• Product Name: (1H-benzo[d][1,2,3]triazol-1-yl)(3-(trifluoromethyl)phenyl)methanone
• Synonyms: (1H-benzo[d][1,2,3]triazol-1-yl)(3-(trifluoromethyl)phenyl)methanone
• CAS NO: 312944-36-8
• Molecular Weight: 291.232
• Mol File: 312944-36-8.mol

Chemical Properties

• CAS DataBase Reference: (1H-benzo[d][1,2,3]triazol-1-yl)(3-(trifluoromethyl)phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1H-benzo[d][1,2,3]triazol-1-yl)(3-(trifluoromethyl)phenyl)methanone(312944-36-8)
• EPA Substance Registry System: (1H-benzo[d][1,2,3]triazol-1-yl)(3-(trifluoromethyl)phenyl)methanone(312944-36-8)

Safety Data

• Hazardous Substances Data: 312944-36-8(Hazardous Substances Data)

Upstream product

• 454-92-2 3-(trifluoromethyl)benzoic acid 
• 95-14-7 1,2,3-Benzotriazole 

Downstream Products

• 403-96-3 1,3-bis(m-α,α,α-trifluorotolyl)urea 
• 2354-93-0 ethyl (3-(trifluoromethyl)phenyl)carbamate 

Relevant articles and documents

An efficient one-pot synthesis of: N, N ′-disubstituted ureas and carbamates from N -acylbenzotriazoles

A facile and high-yielding one-pot synthesis of carbamates and N,N′-disubstituted symmetrical ureas from N-acylbenzotriazoles has been devised. It is believed that, the intermediate acyl-azide undergo Curtius rearrangement and in different solvents gives different products i.e. carbamates in alcohols and N,N′-disubstituted symmetrical urea in THF.

N -Acylbenzotriazoles as Proficient Substrates for an Easy Access to Ureas, Acylureas, Carbamates, and Thiocarbamates via Curtius Rearrangement Using Diphenylphosphoryl Azide (DPPA) as Azide Donor

A diverse range of ureas, N -acylureas, carbamates, and thiocarbamates has been synthesized in good to excellent yields by reacting N -acylbenzotriazoles individually with amines or amides or phenols or thiols in the presence of diphenylphosphoryl azide (DPPA) as a suitable azide donor in anhydrous toluene at 110 °C for 3-4 hours. In this route, DPPA was found to be a good alternative to trimethylsilyl azide and sodium azide for the azide donor in Curtius degradation. The high reaction yields, one-pot and metal-free conditions, straightforward nature, easy handling, use of readily available reagents, and in many cases avoidance of column chromatography are the notable features of the devised protocol.

An Improved N-Acylation of 1 H-Benzotriazole Using 2,2′-Dipyridyl?-di?-sulfide and Triphenylphosphine

A novel path has been developed for the conversion of carboxylic acids into the corresponding N-acylbenzotriazoles by using 2,2′-dipyridyl disulfide/PPh 3 in anhydrous dichloromethane in the presence of 1 H-benzotriazole. Mild reaction conditio

Trichloroisocyanuric Acid Mediated High-Yielding Synthesis of N -Acylbenzotriazoles under Mild Reaction Conditions

N -Acylbenzotriazoles are achieved in good yields from the corresponding carboxylic acids by using only 0.35 equivalent of trichloroisocyanuric acid and 1.2 equivalents of PPh 3. The salient features of the developed reaction path include an ec

A new methodology for the synthesis of N-acylbenzotriazoles

A facile and economic path for an easy access of diverse N-acylbenzotriazoles from carboxylic acid has been devised using NBS/PPh3 in anhydrous dichloromethane. High yield of product was obtained at room temperature in one hour reaction time under mild reaction conditions.