31327-19-2

Upstream product

• 81023-80-5 neopentyloxydiphenyl-1-phenylvinyloxyphosphonium chloride 
• 98-86-2 acetophenone 
• 1499-21-4 Diphenylphosphinic chloride 
• 1707-03-5 diphenyl-phosphinic acid 
• 536-74-3 phenylacetylene 
• 63507-05-1 2,2-dimethyl-1-propyl diphenylphosphinite 
• 532-27-4 1-chloroacetophenone 

Downstream Products

• 100-41-4 ethylbenzene 
• 81238-78-0 (R)-1-phenylethyl diphenylphosphinate 
• 799254-89-0 (S)-1-phensylethyl diphenykphosphinate 
• 1445-91-6 (S)-1-phenylethanol 
• 1517-69-7 (R)-1-phenylethanol 

Relevant academic research and scientific papers

Method for synthesizing alkenyl phosphate compounds

The invention discloses a method for synthesizing alkenyl phosphate compounds with high selectivity. The method includes dissolving a gold catalyst, an alkyne shown as a formula II, and a phosphoric acid compound shown as a formula III into an organic solvent in a nitrogen atmosphere, stirring and reacting the mixture at 25-75 DEG C in a Schlenk reaction tube for 3-10 h, and subjecting an obtainedreaction solution to after-treatment to obtain an alkenyl phosphate compound shown as a formula Iv. The mole ratio of the gold catalyst, the alkyne shown as the formula II, and the phosphoric acid compound shown as the formula III is 0.01-0.05:1-2:1. In the method, the dual-function gold catalyst replaces present expensive ruthenium catalysts or high-toxicity mercury catalysts so that the methodhas advantages of high reaction stereoselectivity, low catalyst toxicity, low catalyst dosage, mild reaction condition, reduced energy consumption, a high yield, high substrate universality, simple and convenient operation, and the like.

Imidazole carbene ligand with amide remote basic functional group as well as synthesis method and application thereof

The invention discloses an imidazole carbene ligand with an alkaline remote functional group, which is a compound shown as a formula (1). The ligand and gold can form a stable metal complex used for catalyzing cyclization reactions, rearrangement reactions, nucleophilic addition reactions and the like. The invention provides a synthetic route of the novel imidazole carbene ligand and a metal complex thereof, achieving simple and efficient alkyne nucleophilic addition. The NHC-Au catalyst is provided with a Lewis acid activation center taking gold as a center and an alkali activation center taking a basic group as a center, and a hindered Lewis acid-base pair can be formed by utilizing a unique linear structure of a monovalent gold complex (ligand-gold-substrate), so that beneficial interaction between the basic functional group and a nucleophilic reagent or substrate is realized, and dual synergistic activation effects of a catalytic system on a reaction transition state are achieved.

Ruthenium-Catalyzed Addition Reaction of Diphenylphosphinic Acid to Terminal Alkynes: Regioselective Synthesis of Alkenyl Diphenylphosphinates

Diphenylphosphinic acid adds across the triple bond of terminal alkynes in the presence of Ru3(CO)12, leading to regioselective formation of alkenyl diphenylphosphinates CH2=C(R).

QUASIPHOSPHONIUM INTERMEDIATES-IV. ISOLATION AND IDENTIFICATION OF INTERMEDIATES IN THE ARBUZOV AND PERKOW REACTIONS OF NEOPENTYL ESTERS OF PHOSPHORUS(III) ACIDS WITH α-HALOGENOACETOPHENONES

Crystalline ketophosphonium bromides have been isolated as intermediates in the reactions of trineopentyl phosphite, dineopentyl phenylphosphonite, and neopentyl diphenylphosphinite with α-bromoacetophenone.Thermal decomposition in solution occurs in each

ASYMMETRIC HYDROGENATION OF ENOL PHOSPHINATES CATALYZED BY A CHIRAL FERROCENYLPHOSPHINE- RHODIUM COMPLEX. ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE SECONDARY ALKYL ALCOHOLS

Catalytic asymmetric synthesis of secondary alkyl alcohols (up to 78 percent ee) was accomplished by asymmetric hydrogenation of enol diphenylphosphinates, derived from prochiral ketones such as acetophenone, 3-methyl-2-butanone, and 2-octanone, in the presence of a cationic rhodium complex of (R)-1-ethanol (BPPFOH).