313345-13-0Relevant academic research and scientific papers
Development of a scaleable process for the synthesis of the A2a agonist, UK-371,104
Challenger, Stephen,Dessi, Yann,Fox, Darrell E.,Hesmondhalgh, Lynsey C.,Pascal, Pierre,Pettman, Alan J.,Smith, Julian D.
, p. 575 - 583 (2008)
The development and utilization of a scaleable process for the manufacture of the A2a agonist UK-371,104 (1) is described. Key steps in the synthesis include (i) a palladium-catalyzed cyanation reaction to prepare the nitrile 10, (ii) a telescoped convers
Purine derivatives
-
Page/Page column 46, (2010/02/11)
The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such compounds as adenosine A2a receptor agonists.
