264608-14-2

Basic information

• Product Name: 2-chloro-N-(2,2-diphenylethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine
• Synonyms: 2-Chloro-N-(2,2-diphenylethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine; 9H-purin-6-amine, 2-chloro-N-(2,2-diphenylethyl)-9-(tetrahydro-2H-pyran-2-yl)-
• CAS NO: 264608-14-2
• Molecular Formula: C₂₄H₂₄ClN₅O
• Molecular Weight: 433.9333
• EINECS: 607-940-6
• Mol File: 264608-14-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 616.21°C at 760 mmHg
• Flash Point: 326.472°C
• Density: 1.35g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.688
• CAS DataBase Reference: 2-chloro-N-(2,2-diphenylethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-(2,2-diphenylethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine(264608-14-2)
• EPA Substance Registry System: 2-chloro-N-(2,2-diphenylethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine(264608-14-2)

Safety Data

• Hazardous Substances Data: 264608-14-2(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 5451-40-1 2,6 dichloropurine 
• 3963-62-0 2,2-Diphenylethylamine 
• 20419-68-5 2,6-dichloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 

Downstream Products

• 264608-15-3 N-(2,2-diphenylethyl)-2-(methylsulfanyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine 
• 313345-09-4 6-[(2,2-diphenylethyl)amino]-9-(tetrahydro-2H-pyran-2-yl)-9H-purine-2-carboxylic acid 
• 313345-14-1 ethyl 6-[(2,2-diphenylethyl)amino]-9-(tetrahydro-2H-pyran-2-yl)-9H-purine-2-carboxylate 
• 264608-17-5 6-[(2,2-diphenylethyl)amino]-9-(tetrahydro-2H-pyran-2-yl)-9H-purine-2-carbonitrile 
• 264608-18-6 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carbonitrile 
• 884654-08-4 (2-chloro-9H-purin-6-yl)-(2,2-diphenyl-ethyl)-amine 
• 313345-13-0 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carboxylic acid 
• 313345-11-8 6-[(2,2-diphenylethyl)amino]-N-[2-(1-piperidinyl)ethyl]-9H-purine-2-carboxamide 
• 380222-94-6 9-{(3AR,4R,6S,6AS)-6-[(ethylamino)carbonyl]-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl}-6-[(2,2-diphenylethyl)amino]-N-{2-[({[1-(2-pyridinyl)-4-piperidinyl]amino}carbonyl)amino]ethyl}-9H-purine-2-carboxamide 
• 1360054-67-6 C₄H₁₁N*C₃₀H₃₂N₆O₆ 
• 380222-90-2 C₃₀H₃₁N₅O₇ 
• 1360054-66-5 N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate 

Relevant articles and documents

Development of a scaleable process for the synthesis of the A2a agonist, UK-371,104

The development and utilization of a scaleable process for the manufacture of the A2a agonist UK-371,104 (1) is described. Key steps in the synthesis include (i) a palladium-catalyzed cyanation reaction to prepare the nitrile 10, (ii) a telescoped convers

Purine derivatives

The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as adenosine A2a receptor agonists.

Purine derivatives

The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as adenosine A2a receptor agonists.