31350-57-9Relevant academic research and scientific papers
A radical coupling reaction of DMSO with sodium arylsulfinates in air:mild utilization of DMSO as C1 resource for the synthesis of arylsulfonyl dibromomethane
Shi, Jie,Tang, Xiao-Dong,Wu, Yan-Cheng,Fang, Jie-Fang,Cao, Liang,Chen, Xiao-Yun,Wang, Zhao-Yang
, p. 25651 - 25655 (2016)
A radical coupling reaction of DMSO with sodium arylsulfinates under air atmosphere to afford arylsulfonyl dibromomethane is described. This transformation provides a novel approach for the utilization of DMSO as a C1 resource with mild temperature without the need for an anaerobic atmosphere.
Controlled α-mono- and α,α-di-halogenation of alkyl sulfones using reagent-solvent halogen bonding
Poteat, Christopher M.,Lindsay, Vincent N. G.
supporting information, p. 2912 - 2915 (2019/03/17)
The direct and selective α-mono-bromination of alkyl sulfones was achieved through base-mediated electrophilic halogenation. The appropriate combination of solvent and electrophilic bromine source was found to be critical to control the nature of the products formed, where reagent-solvent halogen bonding is proposed to control the selectivity via alteration of the effective size of the electrophilic bromine source. Conversely, the α,α-di-brominated sulfones were selectively obtained in good yields following polyhalogenation followed by selective de-halogenation during workup. Both procedures can be applied on gram scale, and the mono-halogenation was successfully extended to the fully selective α-chlorination, α-iodination and α-fluorination of alkyl sulfones.
