313510-75-7Relevant academic research and scientific papers
Synthesis and SAR of heteroaryl-phenyl-substituted pyrazole derivatives as highly selective and potent canine COX-2 inhibitors
Cheng, Hengmiao,Lundy DeMello, Kristin M.,Li, Jin,Sakya, Subas M.,Ando, Kazuo,Kawamura,Kato, Tomoki,Rafka, Robert J.,Jaynes, Burton H.,Ziegler, Carl B.,Stevens, Rod,Lund, Lisa A.,Mann, Donald W.,Kilroy, Carolyn,Haven, Michelle L.,Nimz, Erik L.,Dutra, Jason K.,Li, Chao,Minich, Martha L.,Kolosko, Nicole L.,Petras, Carol,Silvia, Annette M.,Seibel, Scott B.
, p. 2076 - 2080 (2007/10/03)
The discovery of heteroaryl-phenyl-substituted pyrazole derivatives as canine selective COX-2 inhibitors is described. Structure-activity relationship (SAR) studies of this class of compounds led to the identification of compound 1 which demonstrated a ca
Antipsychotic cyclic N-aralkylamines
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, (2008/06/13)
The invention relates to benzene derivatives, to pharmaceutical compositions containing them, to processes for preparing them, and to the method of use thereof in the treatment of psychotic disorders.
Synthesis of phenylglycine derivatives as potent and selective antagonists of group III metabotropic glutamate receptors
Conway, Stuart J,Miller, Jacqueline C,Howson, Patrick A,Clark, Barry P,Jane, David E
, p. 777 - 780 (2007/10/03)
The syntheses of a range of ring and α-substituted 4-phosphonophenylglycines are described. A brief discussion of the antagonist activities of compounds 4-10 on group I, II and III metabotropic glutamate (mGlu) receptors expressed in the neonatal rat spin
