313657-36-2

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 50606-93-4 α-(N-Benzylamino)acetophenone 
• 70-11-1 α-bromoacetophenone 
• 100-46-9 benzylamine 
• 209528-77-8 N-methoxy-N-methyl-N'-benzyl-N'-tert-butyloxycarbonylglycinamide 
• 100-58-3 phenylmagnesium bromide 
• 98-86-2 acetophenone 

Downstream Products

• 1345985-92-3 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 4-nitrobenzenesulfonate 
• 1345985-93-4 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 4-cyanobenzenesulfonate 
• 1345985-94-5 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl naphthalene-1-sulfonate 
• 1345985-95-6 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 2-(trifluoromethyl)benzenesulfonate 
• 1345985-96-7 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl naphthalene-2-sulfonate 
• 1345985-97-8 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 4-methylbenzenesulfonate 
• 1345985-98-9 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 2,4-dinitrobenzenesulfonate 
• 1345985-87-6 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 2,3-dichlorobenzenesulfonate 
• 1345985-88-7 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 3-nitrobenzenesulfonate 
• 1345985-89-8 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 2,6-dichlorobenzenesulfonate 
• 1345985-90-1 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 4-fluorobenzenesulfonate 
• 1345985-91-2 2-(benzyl(tert-butoxycarbonyl)amino)-1-phenylethyl 3,5-dimethylbenzenesulfonate 
• 51096-49-2 (S)-(+)-2-(N-Benzylamino)-1-phenylethanol 
• 27159-38-2 (R)-(-)-N-Benzyl-2-phenylaziridine 

Relevant academic research and scientific papers

Synthesis and 2D QSAR of O-sulphonated β-aminols derivatives as novel antifungal and antibacterial agents

Synthesis of a series of b-aminol derivatives using regioselective opening reaction catalyzed by SiO2 (60-120 mesh) and O-sulphonation in THF-KOH system, comprising tert-butoxycarbonyl at secondary nitrogen and evaluate for various stains of bacteria and fungi. SAR study of synthesized compound using backward regression analysis.

Weinreb amide based synthetic equivalents for convenient access to 4-aryl-1,2,3,4-tetrahydroisoquinolines

New synthetic equivalents, N-methoxy-N-methyl-N′-phenylsulfonyl glycinamide and N-methoxy-N-methyl-N′-benzyl-N′-tert-butyloxy carbonyl glycinamide based on WA functionality were developed for the convenient synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinoline framework. Two simple reactions, N-benzylation and addition of arylmagnesium halide on the WA functionality of the former afforded the key intermediate for convenient synthesis of N-phenylsulfonyl protected 4-aryl-1,2,3,4-tetrahydroisoquinoline, through reduction and acid promoted cyclization. With the latter, the addition of arylmagnesium halide on the WA functionality followed by the same protocol afforded the direct synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinolines in good yields. The acid promoted cyclization step enabled concomitant removal of N-Boc protection.

Enantioselective synthesis of β-hydroxy amines and aziridines using asymmetric transfer hydrogenation of α-amino ketones

Enantioselective transfer hydrogenation of α-amino ketones is an effective method for the asymmetric synthesis of β-hydroxy amines and aziridines.

Enantioselective synthesis of β-hydroxy amines and aziridines using asymmetric transfer hydrogenation of α-amido ketones

A rapid, expedient and enantioselective method for the synthesis of β-hydroxy amines and monosubstituted aziridines in up to 99% e.e., via asymmetric transfer hydrogenation of α-amido ketones, is described. Copyright (C) 2000 Elsevier Science Ltd.