3139-05-7

Basic information

• Product Name: 2,5-DIMETHYL-4-NITROANILINE
• Synonyms: 2,5-DIMETHYL-4-NITROANILINE;4-Nitro-2,5-xylenol;NSC 135201
• CAS NO: 3139-05-7
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 166.18
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 3139-05-7.mol

Chemical Properties

• Melting Point: 134-136
• Boiling Point: 316℃
• Flash Point: 142℃
• Appearance: /
• Density: 1.263
• Vapor Pressure: 0.000226mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 7.70±0.24(Predicted)
• CAS DataBase Reference: 2,5-DIMETHYL-4-NITROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHYL-4-NITROANILINE(3139-05-7)
• EPA Substance Registry System: 2,5-DIMETHYL-4-NITROANILINE(3139-05-7)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 3139-05-7(Hazardous Substances Data)

Usage

Uses

Used in Research Chemicals:
2,5-Dimethyl-4-nitroaniline is used as a research chemical for studying its properties and potential applications in scientific research.
Used in Dye Production:
2,5-Dimethyl-4-nitroaniline is used as an intermediate in the production of dyes, contributing to the coloration of various materials.
Used in Industrial Processes:
2,5-Dimethyl-4-nitroaniline is used in various industrial processes, where its chemical properties are harnessed for specific applications.

InChI:InChI=1/C8H9NO3/c1-5-4-8(10)6(2)3-7(5)9(11)12/h3-4,10H,1-2H3

Upstream product

• 95-87-4 2,5-Dimethylphenol 
• 2593-53-5 2,5-dimethyl-p-benzoquinone 4-oxime 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 20294-63-7 4-Nitroso-2,5-xylenol 
• 3139-06-8 1-methoxy-2,5-dimethyl-4-nitrobenzene 

Downstream Products

• 3139-06-8 1-methoxy-2,5-dimethyl-4-nitrobenzene 
• 147686-54-2 5-(2,5-dimethyl-4-nitrophenoxy)-2,2-dimethylpentanoic acid, methyl ester 

Relevant articles and documents

Amidine compound containing substituent pyrimidine aryl groups and preparation method and application of amidine compound

The invention discloses an amidine compound containing substituent pyrimidine aryl groups. The general formula of the amidine compound is as shown in formula F-1, and the definition of the various substituent groups of the amidine compound is as shown in

Regioselective nitration of aromatic compounds in an aqueous sodium dodecylsulfate and nitric acid medium

An aqueous solution of sodium dodecylsulfate in the presence of dilute nitric acid at room temperature works as a mild medium for the nitration of aromatic compounds with high regioselectivity.

Nitration of substituted phenols by different efficient heterogeneous systems

Nitration of substituted phenols were carried out by the mixture of sodium nitrite and wet SiO2 (50% w/w) in the presence of four different efficient heterogeneous systems: 1) oxalic acid dihydrate (I), 2) sodium hydrogen sulphate (II), 3) aluminum hydrogen sulphate (III) and 4) silica sulphuric acid (IV) in CH2Cl2 at room temperature and high yields. Optimum conditions for theses systems and the regioselectivities of the reactions are reported.

4-amino substituted phenoxyalkyl carboxylic acid, ester, and alcohol derivatives as antihypercholesterolemic and antiatherosclerotic agents

Novel 4-amino substituted phenoxyalkyl carboxylic acid, ester, and alcohol derivatives are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful in preventing the intestinal absorption of cholesterol and thus are useful in the treatment of hypercholesterolemia and atherosclerosis.

FORMATION OF DIENONES ON THE REACTION OF CRESOLS, XYLENOLS, AND 2-NAPHTHOL WITH NITROGEN DIOXIDE: OBSERVATION OF KETO TAUTOMERS OF NITROPHENOLS

Reaction of o- and p-cresol, the xylenols, and 2-naphthol with nitrogen dioxide gives nitrocyclohexadienones and nitrophenols.Secondary nitrodienones, the keto tautomers of the nitrophenols, have been observed in several cases and are intermediates in the formation of the nitrophenols.

ipso Nitration. XXIV. Nitration of 2-methylphenols. Formation and rearrangement of 6-methyl-6-nitrocyclohexa-2,4-dienones

Nitration of o-cresol and some mono-, di-, and trimethyl derivatives in acetic anhydride at -60 deg C gives 6-methyl-6-nitrocyclohexa-2,4-dienones.The dienones are more labile than the isomeric 4-methyl-4-nitrocyclohexa-2,5-dienones and, if the 2-position of the dienone is not blocked, undergo regiospecific rearrangement to 6-nitro-o-cresols. 2,3,6-Trimethyl- and 2,3,5,6-tetramethylphenol also give a 2,5-dienone with nitro attached to a secondary carbon.

Photochemical Nucleophilic Substitution Reactions of Methyl Substituted Derivatives of p- and o-Nitroanisole

Photosubstitution reactions of several methyl substituted derivatives of p- and o-nitroanisole with hydroxide ion were investigated.The methyl substituent seemed to show an uncertain (probably electronic) effect in addition to the steric effect for the replacement of both the methoxy and the nitro groups.Mainly, the replacement reaction of the nitro group is discussed.

IPSO NITRATION: NITRATION OF 2-ALKYLPHENOLS IN ACETIC ANHYDRIDE. FORMATION OF 6-ALKYL-6-NITROCYCLOHEXA-2,4-DIENONES

Low temperature nitration of 2-alkylphenols in acetic anhydride gives 6-alkyl-6-nitrocyclohexa-2,4-dienones.The dienones undergo a regiospecific rearrangement to give o-nitrophenols