3139-10-4

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
6-Methyl-5-Methoxy indole is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals for its ability to contribute to the development of various chemical compounds that have medicinal or agricultural applications.
Used in Fragrance and Flavor Production:
6-Methyl-5-Methoxy indole is used as a component in the production of fragrances and flavors due to its characteristic odor, adding unique scents to a variety of products in these industries.
Further Research:
6-Methyl-5-Methoxy indole's role in biological systems and potential health effects have not been extensively studied. Further research is needed to understand its properties and explore additional potential applications in various fields.

Upstream product

• 3139-06-8 1-methoxy-2,5-dimethyl-4-nitrobenzene 

Relevant academic research and scientific papers

(AZA)INDOLE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES

The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal serum uric acid level which has a uricosuric activity or the like. The present invention relates to (aza)indole derivatives represented by the following general formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of serum uric acid level, prodrugs thereof, or salts thereof. In the formula (I), T represents nitro or cyano and the like; ring J represents aryl or heteroaryl and the like; Q represents carboxy or 5-tetazolyl and the like; Y represents H, OH, NH2, halogen, nitro, alkyl, alkoxy and the like; X1, X2 and X3 independently represent CR2 or N; R1 and R2 independently represent halogen, cyano, haloalkyl, A-D-E-G, -N(-D-E-G)2 and the like, in the formula, A represents a single bond, O, S and the like; D and G independently represent optionally substituted alkylene, cycloalkylene, heterocycloalkylene, arylene, heteroarylene and the like; E represents a single bond, O, S, COO, SO2 and the like.

Studies on Several 7-Substituted N,N-Dimethyltryptamines

Several 7-substituted derivatives of N,N-dimethyltryptamine (DMT) were prepared and evaluated in the rat fundus serotonin receptor assay and in a behavioral (discriminative stimulus) assay in rats.Both 7-Me- and 5-Ome-7-Me-DMT possess a higher pA2, and 5,7-(OMe)2-DMT a lower pA2, than that of DMT itself.Like DMT, all three of these compounds produce behavioral effects in rats which are similar to those of the hallucinogen 5-OMe-DMT.Although 7-Et- and 7-Br-DMT possess a higher serotonin receptor affinity than DMT, neither produce behavioral effects which parallelthose of 5-OMe-DMT.In contrast, 6-OMe-DMT and its 5-OMe derivative do not interact with the serotonin receptors in a competitive manner and are inactive in the discriminative stimulus assay.