313956-72-8

Upstream product

• 313956-73-9 3-[4-(4-bromo-phenyl)-thiazol-2-yl]-2-imino-2H-chromen-7-ol 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 94833-31-5 2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]acetonitrile 
• 99-73-0 para-bromophenacyl bromide 

Relevant academic research and scientific papers

Chemistry of 3-hetarylcoumarins. 2. 3-(2-thiazolyl)coumarins

3-(2-Thiazolyl)coumarins were obtained by the reaction of substituted salicylaldehydes with 2-thiazolylacetonitriles. Methylation, acylation, and aminomethylation were studied for the 7-hydroxy-substituted products.

DERIVATIVES OF CHROMEN-2-ONE AS INHIBITORS OF VEGF PRODUCTION IN MAMMALIAN CELLS

The compounds of formula (I) wherein A and R1-R5 are as defined in the description, are inhibitors of Vascular Endothelial Growth Factor and are useful as angiogenesis inhibitors and antiproliferative agents.