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4-(4-BROMOPHENYL)-2-THIAZOLEACETONITRIL&, with the molecular formula C11H7BrN2S, is a thiazole derivative featuring a bromophenyl group attached to the 4-position of the thiazole ring. This chemical compound is widely recognized for its role in organic synthesis and pharmaceutical research, where it serves as a building block for creating various biologically active molecules and pharmaceutical drugs.

94833-31-5

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94833-31-5 Usage

Uses

Used in Organic Synthesis:
4-(4-BROMOPHENYL)-2-THIAZOLEACETONITRIL& is used as a key intermediate in organic synthesis for the development of complex organic molecules. Its unique structure allows for the formation of carbon-carbon and carbon-nitrogen bonds, which are crucial for constructing a diverse range of chemical compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-(4-BROMOPHENYL)-2-THIAZOLEACETONITRIL& is utilized as a building block for the synthesis of biologically active molecules and pharmaceutical drugs. Its presence in these molecules can potentially enhance their therapeutic effects and contribute to the development of new medications.
Used in Medicinal Chemistry Research:
4-(4-BROMOPHENYL)-2-THIAZOLEACETONITRIL& has been studied for its potential antiviral and anticancer properties, making it a valuable compound for medicinal chemistry research. Its ability to target specific biological pathways and mechanisms may lead to the discovery of novel treatments for various diseases.
Used as a Reagent in Chemical Reactions:
4-(4-BROMOPHENYL)-2-THIAZOLEACETONITRIL& also serves as a reagent in chemical reactions, facilitating the formation of essential carbon-carbon and carbon-nitrogen bonds. Its role in these reactions is vital for the synthesis of a wide array of chemical products, including those used in various industries such as pharmaceuticals, materials science, and agrochemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 94833-31-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,8,3 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 94833-31:
(7*9)+(6*4)+(5*8)+(4*3)+(3*3)+(2*3)+(1*1)=155
155 % 10 = 5
So 94833-31-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H7BrN2S/c12-9-3-1-8(2-4-9)10-7-15-11(14-10)5-6-13/h1-4,7H,5H2

94833-31-5 Well-known Company Product Price

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  • Aldrich

  • (653497)  4-(4-Bromophenyl)-2-thiazoleacetonitrile  97%

  • 94833-31-5

  • 653497-1G

  • 990.99CNY

  • Detail
  • Aldrich

  • (653497)  4-(4-Bromophenyl)-2-thiazoleacetonitrile  97%

  • 94833-31-5

  • 653497-5G

  • 3,664.44CNY

  • Detail

94833-31-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]acetonitrile

1.2 Other means of identification

Product number -
Other names 4-(4-Bromphenyl)-2-cyanomethylthiazol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:94833-31-5 SDS

94833-31-5Relevant academic research and scientific papers

COMPOUNDS AND METHODS for the inhibition of HDAC

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Paragraph 0129-0130; 0221-0222; 0319-0320, (2015/11/24)

Disclosed are compounds having the formula: wherein X1, X2, X3, R1, R2, R3, R4, Y, A, Z, L and n are as defined herein, and methods of making and using the same.

Synthesis of novel 3-(1,3-thiazol-2-yl)-7,8-dihydroquinoline-2,5(1H,6H)- diones

Dzhavakhishvili,Gorobets,Chernenko,Musatov,Desenko

experimental part, p. 422 - 427 (2009/06/05)

An efficient method for the synthesis of novel 3-(1,3-thiazol-2-yl)-7,8- dihydroquinoline-2,5(1H,6H)-diones from various 2- dimethylaminomethylidenecyclohexane-1,3-diones, (1,3-thiazol-2-yl)acetonitriles, and dimethylformamide dimethyl acetal was developed. These transformations proceeded through intermediate 2-[2-(4-aryl-1,3-thiazol-2-yl)-2-cyanoethenyl]-3- oxocyclohex-1-en-1-olates. They were isolated as piperidinium salts and used in further heterocyclization reactions with aromatic amines, giving novel 1-aryl-3-(1,3-thiazol-2-yl)-7,8-dihydroquinoline-2,5(1H,6H)-diones. These compounds were also obtained by preparative three-step "one pot" synthesis under controlled microwave irradiation.

DERIVATIVES OF CHROMEN-2-ONE AS INHIBITORS OF VEGF PRODUCTION IN MAMMALIAN CELLS

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Page 66 - 67, (2008/06/13)

The compounds of formula (I) wherein A and R1-R5 are as defined in the description, are inhibitors of Vascular Endothelial Growth Factor and are useful as angiogenesis inhibitors and antiproliferative agents.

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