314020-44-5

Basic information

• Product Name: 7H-Pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione, 8-(2,6-diethyl-4-methylphenyl)tetrahydro-
• CAS NO: 314020-44-5
• Molecular Formula: C18H24N2O3
• Molecular Weight: 316.4
• Mol File: 314020-44-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 7H-Pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione, 8-(2,6-diethyl-4-methylphenyl)tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 7H-Pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione, 8-(2,6-diethyl-4-methylphenyl)tetrahydro-(314020-44-5)
• EPA Substance Registry System: 7H-Pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione, 8-(2,6-diethyl-4-methylphenyl)tetrahydro-(314020-44-5)

Safety Data

• Hazardous Substances Data: 314020-44-5(Hazardous Substances Data)

Upstream product

• 314084-61-2 1-bromo-2,6-diethyl-4-methylbenzene 
• 405281-14-3 hexahydro-1,4,5-oxadiazepine dihydrochloride 
• 328932-70-3 2-(2,6-diethyl-4-methylphenyl)malonic acid diethyl ester 
• 1176272-84-6 (2,6-diethyl-4-methylphenyl)acetic acid methyl ester 
• 34604-52-9 diethylene glycol dimesylate 
• 243973-70-8 1,4,5-oxadiazepane hydrobromide 
• 243973-70-8 hexahydro[1,4,5]-oxadiazepine dihydrobromide 
• 24544-08-9 2,6-diethyl-4-methylaniline 
• 243973-72-0 (2,6-diethyl-4-methylphenyl)malonic acid dimethyl ester 

Downstream Products

• 243973-20-8 pinoxaden 

Relevant articles and documents

Method for preparing pinoxaden intermediate through micro-channel

The invention relates to a method for preparing a pinoxaden intermediate through a micro-channel. Intermediates 2, 6-diethyl-4-methyl phenyl diethyl malonate and [1, 4, 5] oxadiazepane dihydrobromideare prepared from 2, 6-diethyl-4-methylbenzenemalononitr

Method for synthesizing pinoxaden through 2,6-diethyl-4-methylphenyl malonate

The invention relates to the field of organic synthesis, in particular to a method for synthesizing pinoxaden through 2,6-diethyl-4-methylphenyl malonate. The method comprises the following steps that1, the 2,6-diethyl-4-methylphenyl malonate reacts with hydrazine hydrate to form 4-(2,6-diethyl-4-methyl)-1,2,4,5-tetrahydropyrazole-3,5-diketone; 2, the 4-(2,6-diethyl-4-methyl)-1,2,4,5-tetrahydropyrazole-3,5-diketone is subjected to cyclization with diethylene glycol dimethanesulfonate or dibromo-diethylene glycol under the effect of triethylamine to generate 8-(2,6-diethyl-4-methylbenzene)-1,2,4,5-tetrahydropyrazole[1,2-d][1,4,5]oxo-dinitrogen-7,9-diketone; 3, the 8-(2,6-diethyl-4-methylbenzene)-1,2,4,5-tetrahydropyrazole[1,2-d][1,4,5]oxo-dinitrogen-7,9-diketone reacts with pivaloyl chloride under an alkaline condition to generate the pinoxaden. The method has the advantage that the use of expensive noble metal catalysts and hypertoxic cyaniding reagents is avoided, the adopted reagents are environmentally friendly, the cost is lowered, the process is simplified, the yield is high, the defects of the prior art are overcome, and the method is suitable for large-scale industrial production.

CHEMICAL PROCESS FOR THE SYNTHESIS OF HERBICIDAL PYRAZOLIDINEDIONE COMPOUNDS

The present invention relates to a novel process for the synthesis of herbicidal pyrazolidinedione compounds. In particular, a process for the preparation of a compound of formula (I), wherein R1, R2 and R3 are as defined herein. The present invention further relates to novel intermediate compounds utilized in said process, and methods for preparing said intermediate compounds.